Anaplastic ganglioglioma becoming symptomatic in the third trimester of pregnancy

Authors

  • Stylianos Pikis Department of Neurosurgery, Korgialenio Benakio Red Cross Hospital of Athens, Athens, Greece
  • Tigran Petrosyan Department of Neurosurgery, Korgialenio Benakio Red Cross Hospital of Athens, Athens, Greece
  • Kalliopi Diamantopoulou Department of Pathology, Korgialenio Benakio Red Cross Hospital of Athens, Athens, Greece
  • Christos Kelesis Department of Neurosurgery, Korgialenio Benakio Red Cross Hospital of Athens, Athens, Greece

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20170608

Keywords:

Anaplastic ganglioglioma, Brain tumor, Diagnosis, Pregnancy

Abstract

Intracranial tumors are rare in pregnancy and may present a diagnostic and therapeutic challenge. We report on a 34-year-old female who presented with new-onset partial seizures hours following delivery due to a left frontal space occupying lesion. Urgent surgical resection of the lesion was performed and histopathologic evaluation revealed anaplastic ganglioglioma. Post-operatively the patient received radiotherapy and temozolamide chemotherapy. She reported a three-month history of progressive headache and nausea which were falsely attributed to pregnancy both by the patient and her treating physician leading to a delay in diagnosis and management. In the pregnant patient presenting with neurological symptoms a high index of suspicion and a thorough physical examination is required to identify those patients at risk of intracranial pathology.

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References

Ravindra VM, Braca III JA, Jensen RL, Duckworth EA. Management of intracranial pathology during pregnancy: Case example and review of management strategies. Surg Neurol Int. 2015;6:43.

Lucas Jr JT, Huang AJ, Mott RT, Lesser GJ, Tatter SB, Chan MD. Anaplastic ganglioglioma: a report of three cases and review of the literature. J Neuro-oncol 2015;123(1):171-7.

Knafo S, Goutagny S, Pallud J. Increased growth rate of a WHO grade I ganglioglioma during pregnancy. British J Neurosurg. 2013;27(1):119-121.

Pikis S, Cohen JE, Rosenthal G, Barzilay Y, Kaplan L, Shoshan Y, et al. Spinal meningioma becoming symptomatic in the third trimester of pregnancy. J Clin Neurosci. 2013;20(12):1797-9.

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Published

2017-02-19

How to Cite

Pikis, S., Petrosyan, T., Diamantopoulou, K., & Kelesis, C. (2017). Anaplastic ganglioglioma becoming symptomatic in the third trimester of pregnancy. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 6(3), 1158–1160. https://doi.org/10.18203/2320-1770.ijrcog20170608

Issue

Section

Case Reports