Three-dimensional follicular assessment: a review of technique and indications
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20241799Keywords:
Assisted reproductive techniques, Three-dimensional ultrasound, Follicular maturity assessment, Endometrial receptivityAbstract
Follicular maturity assessment and tracking are employed to ascertain mature oocytes’ presence and assess the response to ovarian stimulation. This step is crucial to ensure successful outcomes during assisted reproductive techniques. Currently, two-dimensional (2-D) transvaginal ultrasound is performed to monitor follicle growth and determine the optimal time for administration of human chorionic gonadotropin (hCG) hormone. However, the accurate follicle size, count, and multi-follicle maturity assessment require significant expertise and negligible inter-observer variations to maintain the reliability and validity of the measurements. 2-D ultrasound allows only an approximation of the actual follicular volume; therefore, it cannot be used to define standards for follicular maturity assessment. With the improvement of ultrasonography imaging technologies and the supporting software, it is now possible to acquire three-dimensional data sets and perform precise estimation of absolute dimensions, volumes, and mean dimensions of even complex structured follicles. This paper aimed to provide an in-depth review of the use of 3D ultrasound (3D-US) in reproductive medicine and combines an overview of the technique of performing a 3D-US for a fast, valid, objective, and reliable follicular assessment.
Metrics
References
Murtinger M, Zech NH. 3D Ultrasound for Follicle Monitoring in ART. In: Stadtmauer L, Tur-Kaspa I, eds. Ultrasound Imaging in Reproductive Medicine. New York, NY: Springer; 2014.
Fauser BC. Follicular development and oocyte maturation in hypogonadotrophic women employing recombinant follicle-stimulating hormone: the role of oestradiol. Hum Reprod Update. 1997;3:101-8.
Panchal S, Nagori CB. Pre-hCG 3D and 3D power Doppler assessment of the follicle for improving pregnancy rates in intrauterine insemination cycles. J Hum Reprod Sci. 2009;2:62-7.
Zackova T, Jarvela IY, Mardesic T. The role of 3D ultrasound in assessment of endometrial receptivity and follicular vascularity to predict the quality oocyte. InTech Open; 2011.
Mahadevan M, Chalder K, Wiseman D, Leader A, Taylor PJ. Evidence for an absence of deleterious effects of ultrasound on human oocytes. J In Vitro Fert Embryo Transf. 1987;4:277-80.
Rodriguez A, Guillen J, Blazquez A. Follicular tracking with three-dimensional ultrasound increases ovarian stimulation efficiency in oocyte donors. Ultras Obstetr Gynecol. 2012.
Norton SJ, Linzer M. Ultrasonic refl ectivity imaging in three dimensions: reconstruction with spherical transducer arrays. Ultrason Imaging. 1979;1:210-31.
Lee W, Gonçalves LF, Espinoza J, Romero R. Inversion mode: a new volume analysis tool for 3-dimensional ultrasonography. J Ultrasound Med. 2005;24:201-7.
Penzias AS, Emmi AM, Dubey AK, Layman LC, DeCherney AH, Reindollar RH. Ultrasound prediction of follicle volume: is the mean diameter reflective? Fertil Steril. 1994;62:1274-6.
Jacobs HS. Polycystic ovaries and polycystic ovary syndrome. Gynecol Endocrinol. 1987;1:113-31.
Adams J, Polson DW, Franks S. Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. Br Med J. 1986;293:355-9.
Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81:19-25.
Pascual MA, Graupera B, Hereter L. Assessment of ovarian vascularization in the polycystic ovary by three-dimensional power Doppler ultrasonography. Gynecol Endocrinol. 2008;24:631-6.
Wittmaack FM, Kreger DO, Blasco L, Tureck RW, Mastroianni L, Lessey BA. Effect of follicular size on oocyte retrieval, fertilization, cleavage, and embryo quality in vitro fertilization cycles: A 6-year data collection. Fertil Steril. 1994;62:1205-10.
Rackow BW, Arici A. Reproductive performance of women with müllerian anomalies. Curr Opin Obstet Gynecol. 2007;19:229-37.
Airoldi J, Berghella V, Sehdev H, Ludmir J. Transvaginal ultrasonography of the cervix to predict preterm birth in women with uterine anomalies. Obstet Gynecol. 2005;106:553-6.
Gruboeck K, Jurkovic D, Lawton F, Savvas M, Tailor A, Campbell S. The diagnostic value of endometrial thickness and volume measurements by threedimensional ultrasound in patients with postmenopausal bleeding. Ultrasound Obstet Gynecol. 1996;8:272-6.
Raga F, Bonilla-Musoles F, Blanes J, Osborne NG. Congenital Müllerian anomalies: diagnostic accuracy of three-dimensional ultrasound. Fertil Steril. 1996;65:523-8.
Bergh PA, Navot D. The impact of embryonic development and endometrial maturity on the timing of implantation. Fertil Steril. 1992;58:537-42.
Raine-Fenning N, Campbell B, Collier J, Brincat M, Johnson I. The reproducibility of endometrial volume acquisition and measurement with the VOCALimaging program. Ultrasound Obstet Gynecol. 2002;19:69-75.
Gougeon A. Regulation of ovarian follicular development in primates: facts and hypotheses. Endocr Rev. 1996;17:121-55.
Järvelä IY, Mason HD, Sladkevicius P, Kelly S, Ojha K, Campbell S, et al. Characterization of normal and polycystic ovaries using three-dimensional power Doppler ultrasonography. J Assist Reprod Genet. 2002;19:582-90.
Allemand MC, Tummon IS, Phy JL, Foong SC, Dumesic DA, Session DR. Diagnosis of polycystic ovaries by three-dimensional transvaginal ultrasound. Fertil Steril. 2006;85:214-9.
Jayaprakasan K, Campbell BK, Clewes JS. Three-dimensional ultrasound improves the interobserver reliability of antral follicle counts and facilitates increased clinical workflow. Ultrasound Obstet Gynecol. 2008;31:439-444.
Raine-Fenning NJ, Lam PM. Assessment of ovarian reserve using the inversion mode. Ultrasound Obstet Gynecol. 2006;27:104-6.
Peres Fagundes PA, Chapon R, Olsen PR. Evaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormone. Reprod Biol Endocrinol. 2017;16:96.
Forman RG, Robinson J, Yudkin P, Egan D, Reynolds K, Barlow DH. What is the true follicular diameter: an assessment of the reproducibility of transvaginal ultrasound monitoring in stimulated cycles. Fertil Steril. 1991;56:89-92.
Feichtinger W. Transvaginal three-dimensional imaging for evaluation and treatment of infertility. In: Merz E, eds. 3D ultrasound in obstetrics and Gynecology. Philadelphia: Lippincott Williams and Wilkins; 1998:37-43.
Sherbahn R, Deutch T. Follicular measurements using a computerized 3D ultrasound system (SonoAVC) for monitoring ovarian stimulation for IVF is effective and efficient. Fertil Steril. 2009;92(3):118.
Merce LT. Ultrasound markers of implantation. Ultra Rev Obstet Gynecol. 2002;2:1102-3.
Merce LT, Barco MJ, Kupesic S, Kurjak A. 2D and 3D power Doppler ultrasound from ovulation to implantation. In: Kurjak A, Chervenak F, eds. Textbook of prenatal medicine. London: Parthenon Publishing; 2005:20.