A rare case on ovarian hyperstimulation syndrome in a spontaneous singleton pregnancy

Authors

  • Neha . Department of Obstetrics and Gynaecology, RNT Medical College, Udaipur, Rajasthan, India
  • Madhubala Chauhan Department of Obstetrics and Gynaecology, RNT Medical College, Udaipur, Rajasthan, India
  • Divya Chaudhary Department of Obstetrics and Gynaecology, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20241796

Keywords:

Ascites, CA-125, Dopamine agonist, OHSS

Abstract

Spontaneous form of ovarian hyperstimulation syndrome in pregnancy (OHSS) is extremely rare and characterized by gastro-intestinal symptoms and complication of shift of fluid in the third space. It is often associated with multiple gestations, hypothyroidism, polycystic ovarian syndrome and molar pregnancy. Treatment depends on the patient’s clinical condition. The aim of this case report is to bring into light a case of spontaneous OHSS in a healthy Indian pregnant woman that presented with pain abdomen, abdominal distension and vomiting at 14 weeks of gestation without any of the above-mentioned risk factors. Ultrasonography showed a single viable intrauterine pregnancy along with bilateral enlarged cystic ovaries, ascites and raised CA-125 levels. There was no history of ovulation induction in present and previous pregnancy. We successfully managed the patient conservatively with Dopamine agonist Cabergoline and she delivered a healthy baby at 33 weeks. Although spontaneous OHSS is a rare entity, it should be included in differential diagnosis of acute abdomen in pregnant women. OHSS can lead to life threatening complications, early diagnosis is required for proper management.

 

 

References

Namavar Jahromi B, Parsanezhad ME, Shomali Z, Bakhshai P, Alborzi M, Moin Vaziri N, et al. Ovarian Hyperstimulation Syndrome: A Narrative Review of Its Pathophysiology, Risk Factors, Prevention, Classification, and Management. Iran J Med Sci. 2018;43(3):248-60.

The Management of Ovarian Hyperstimulation Syndrome (Green-top Guideline No. 5). Available at: https://www.rcog.org.uk/globalassets/documents/gui delines/green-top-guidelines/gtg_5_ohss.pdf. Accessed on 09 March 2024.

Nwafor NN, Nyoyoko NP. Spontaneous Ovarian Hyperstimulation Syndrome: A Report of Two Cases from Different Pathogenesis. Niger Med J. 2020;61(5):269-72.

Manalai G, Shirzai A, Aalemi AK. High Dose Cabergoline in Management of Bilateral Ovarian Hyperstimulation Syndrome: A Case Report. Int Med Case Rep J. 2021;14:557-61.

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Published

2024-06-27

Issue

Section

Case Reports