Seasonal variation of human semen parameters: a retrospective study in Chennai, Tamil Nadu
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20242486Keywords:
Temperature, Semen analysis, Season, Microscopic examination, Chennai, Macroscopic examinationAbstract
Background: Infertility in humans is a prevalent disorder that arises from several primary or secondary reasons. Regarding the latter, many seasonal and meteorological trends have been proposed as potential contributors. This study set out to determine whether the functional properties of semen samples kept in a secondary centre database showed any signs of a potential seasonal trend.
Methods: Retrospective analysis was performed on the 1830 consecutive sperm analysis reports that were gathered at the Institute of Reproductive Medicine and Women's Health over the course of a year (2020-2024). Microscopic, macroscopic examinations were included in the reports. Season of sample collection was used to examine data for various parameters. The assessment of continuous variables should be done using the ANOVA test. Additionally, a regression analysis and chi-squared will be carried out to determine the significant variation caused by season on semen parameter.
Results: Seasonal variations significantly impact sperm concentration and total sperm count, with temperature changes across seasons being a key factor. However, motility, morphology, and defect parameters remain stable and unaffected by temperature. Environmental factors like temperature should be considered in fertility assessments and treatments.
Conclusions: In conclusion, this thesis demonstrates that semen quality is significantly influenced by seasonal variations, with cooler temperatures associated with improved sperm concentration and total count, as indicated by statistically significant p values (p<0.05) for these parameters. The p values for sperm concentration (p=0.0280) and total sperm count (p=0.0363) confirm a significant relationship with seasonal temperature changes. In contrast, parameters such as motility and morphology remain relatively stable across seasons, as evidenced by non-significant p values (p>0.05).
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References
Agarwal A, Mulgund A, Hamada A, Chyatte MR. A unique view on male infertility around the globe. Reproduct Biol Endocrinol. 2015;13:37.
World Health Organization. WHO Laboratory Manual for the Examination and Processing of Human Semen. 5th ed. Cambridge: Cambridge University Press; 2010.
Levine H, Jørgensen N, Martino-Andrade A, Mendiola J, Weksler-Derri D, Mindlis I, et al. Temporal trends in sperm count: a systematic review and meta-regression analysis. Human Reproduction Update. 2017;23(6):646-59.
Sharpe RM. Environmental/lifestyle effects on spermatogenesis. Philosophical Transactions Royal Society B: Biolog Sci. 2010;365(1546):1697-712.
Fedder J, Hansen LA, Hjort T, Parner ET. Male infertility and age-dependent alterations in semen quality. Andrologia. 2018;50.
Talebi AR, Sadeghi S, Valojerdi MR, Fesahat F. Effects of environmental temperature on sperm parameters and chromatin integrity in fertile and infertile men. J Reprod Infertil. 2013;14:104-10.
Demirelli E, Karagöz A, Öğreden E, Oğuz U, Vural A, Aksu M, et al. The relationship between the severity of erectile dysfunction and aortic stiffness. Andrologia. 2020;52(4):e13544.
Sánchez V, Wistuba J, Mallidis C. Semen analysis: update on clinical value, current needs and future perspectives. Reproduction. 2013;146:R249-58.
Handelsman DJ, Brinkworth MH. Environmental influences on male reproductive health. Androl Male Reproduct Health Dysfunc. 2010;365-89.
Ozelci R, Yılmaz S, Dilbaz B, Akpınar F, Akdag Cırık D, Dilbaz S, et al. Seasonal variation of human sperm cells among 4,422 semen samples: A retrospective study in Turkey. Syst Biol Reprod Med. 2016;62:379-86.
Centola GM, Eberly S. Seasonal variations and age-related changes in human sperm count, motility, motion parameters, morphology, and white blood cell concentration. Fertil Steril. 1999;72:803-8.
Wang X, Tian X, Ye B, Zhang Y, Zhang X, Huang S, et al. The association between ambient temperature and sperm quality in Wuhan, China. Environ Health. 2020;19:44.
Balhara K, Singh S, Sharma S. Seasonal variation in semen quality: effect of temperature: a study in North India. Int J Reprod Contracept Obstet Gynecol. 2022;11:601-6.
Chen H, Wang L, Liu Y. Effects of seasonal variations on sperm quality and reproductive health. Andrology. 2021;9:1234-42.
De Giorgi A, Volpi RDS, Tiseo R, Pala M, Manfredini R, Fabbian F. Seasonal variation of human semen parameters: A retrospective study in Italy. Chronobiol Int. 2015;32:711-6.
Deng W, Zhang T, Li H. Effects of high ambient temperatures on semen quality: A review. Asian J Androl. 2019;21:541-8.
Malathi A, Iyer RP, Mohan R, Balakrishnan S. Impact of seasonal variations on semen parameters: A retrospective analysis of data from subjects attending a tertiary care fertility centre. J Hum Reprod Sci. 2023;16:114-20.
Ramírez ND, Tissera A, Molina R, Olmedo J, Molina HG, Mangeaud A, et al. Fluctuations in seminal quality throughout the year: How do temperature, humidity and atmospheric pressure impact on human sperm quality? J Hum Reprod Sci. 2023;16:185-94.
Santi D, Magnani E, Michelangeli M, Grassi R, Vecchi B, Pedroni G, et al. Seasonal variation of semen parameters correlates with environmental temperature and air pollution: A big data analysis over 6 years. Environ Pollut. 2018;235:806-13.
Verón GL, Tissera AD, Bello R, Estofan GM, Hernández M, Beltramone F, et al. Association between meteorological variables and semen quality: A retrospective study. Int J Biometeorol. 2021;65:1399-414.
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