A study on feto-maternal outcome in patients with preterm premature rupture of membranes

Niki Shah; Vipul S. Patel; Anisa Shaikh

doi:10.18203/2320-1770.ijrcog20241983

Authors

Niki Shah Department of Obstetrics and Gynaecology, Dr. M. K. Shah Medical College and Research Centre, Ahmedabad, Gujarat, India
Vipul S. Patel Department of Obstetrics and Gynaecology, Dr. M. K. Shah Medical College and Research Centre, Ahmedabad, Gujarat, India
Anisa Shaikh Department of Obstetrics and Gynaecology, Dr. M. K. Shah Medical College and Research Centre, Ahmedabad, Gujarat, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20241983

Keywords:

Preterm premature rupture of membranes, Chorioamnionitis, Maternal outcome, Neonatal outcome

Abstract

Background: Preterm premature rupture of membranes (PPROM) is rupture of fetal membranes prior to labor in pregnancies between 28-37 weeks. PPROM is associated with significant maternal and neonatal morbidity or mortality. The present study was conducted to evaluate risk factor and etiology of PPROM and its fetomaternal effect in tertiary care hospital.

Methods: A cross-sectional study was conducted in the department of obstetrics and gynaecology, SMS Hospital, Ahemdabad. From August 2023 to February 2024.The study included 50 pregnant women between 28-37 weeks gestation with PPROM were subjected to detailed history and examination. Each patient was followed till her delivery and fetomaternal outcome was recorded.

Results: PPROM is a fair complication of pregnancy. 80% were belongs to 20-29 age, 70% were unbooked, 76% from low SE-class, 68% with gestational age of 34-36 weeks. Vaginal delivery was common 58%. The babies born to mothers with PPROM more in weight of 2-2.5 kg (48%). 34 had no risk factors to develop PPROM. Most common etiology for PPROM infection 16% and malpresentation 10%. Most of the mothers with PPROM had no complications. 17 (34%) babies required NICU admissions for complaints of premturity, respiratory distress, birth asphyxia, and sepsis. RDS was most common neonatal complication. 2 neonatal deaths in this study due to RDS and prematurity.

Conclusions: Effective PPROM Mx involves evaluating the risks and advantage of conservative Mx strategies. Whenever possible, Rx should be focused towards prophylactic use of antibiotics and steroids during pregnancy can reduce fetal and mother morbidity and mortality. Termination of pregnancy should be considered at the 1^st sign of chorioamnionitis.

Metrics

Metrics Loading ...

References

Dayal S, Hong Pete RL. Premature rupture of Membranes, 12th edition. Treasure Island, Florida: Stat Pearls Publishing. 2020.

Misra R. Ian Donalds Practical Obstetric problems, 8th edition. Wolters Kluwer India Pvt Ltd. 2020.

Assefa NE, Berhe H, Girma F, Berhe K, Berhe YZ, Gebreheat G, et al. Risk factors of premature rupture of membranes in public hospitals at Mekele city, Tigray, a case control study. BMC Pregnancy Childbirth. 2018;18:1-7.

Chandra I, Sun L. Third trimester preterm and term premature rupture of membranes: Is there any difference in maternal characteristics and pregnancy outcomes? J Chinese Med Assoc. 2017;12(6):1-5.

Emechebe CI, Njoku CO, Anachuna K, Udofia U. Determinants and complications of pre-labor rupture of membranes (PROM) at the University of Calabar teaching Hospital (UCTH), Calabar, Nigeria. Scholars J Appl Med Sci. 2015;3(5B):1912-7.

Jiwane KA. Antenatal vaginal examination as a cause of PROM. J Obstet Gynaecol India. 1991;41:337.

Rana M, Patra S, Puri M, Trivedi SS. Fetomaternal Outcome in Preterm Premature Rupture of Mem- brane. Int J Infertil Fetal Med. 2014;5(1):18-21.

Noor S, Nazar AF, Bashir R, Sultana R. Prevalance of PPROM and its outcome. J Ayub Med Coll Abbottabad. 2007;19(4):14-7.

Thapa A, Medhi R. Fetal and maternal outcomes and risk factors associated with preterm prelabour rupture of membrane. Int J Res Med Sci. 2023;11:2090-7.

Jain A, Paul M. A study of maternal outcome in term premature rupture of membranes in a tertiary care hospital. Int J Reprod Contracept Obstet Gynecol. 2020;9:2953-8.

Hill LM. Prevalence of breech presentation by gestational age. Am J Perinatol. 1990;7:92-3.

Singh N, Pattnaik L, Panda SR, Jena P, Panda J. Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India. Cureus. 2022;14(5):e25533.