A retrospective study of mullerian anomalies and their outcome in pregnancy in a tertiary care center

Authors

  • Chinthala Sai Lakshmi Shreya Department of Obstetrics and Gynecology, Sri Devaraj URS Medical College, Tamaka, Kolar, Karnataka, India
  • Rathnamma Papanna Department of Obstetrics and Gynecology, Sri Devaraj URS Medical College, Tamaka, Kolar, Karnataka, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20243166

Keywords:

Mullerian anomaly, Abortions, Pregnancy outcome, Malpresentations

Abstract

Background: Uterine abnormalities resulting from aberrant embryonic development, fusion, or resorption of the Mullerian ducts, the primitive homologue of the female reproductive tract, are known as congenital uterine malformations. In the reproductive age range, its prevalence is 2-4%, and in women who have had unfavourable reproductive outcomes, it is 5-25%. These deformities are linked to several obstetrical outcomes, including fetal growth limitation, fetal death, premature rupture of the membranes, preterm delivery, and a higher risk of ectopic pregnancy. They are also linked to first and second-trimester abortions. This study aimed to observe the different types of Mullerian anomalies and their outcome among pregnant women.

Methods: A retrospective observational study was carried out in the Department of Obstetrics and Gynecology in tertiary care hospital from May 2022 to March 2024.

Results: During this study, malpresentations found in bicornuate, unicornuate, didelphys uterus. Abortions were reported in 25% of cases.

Conclusions: A high suspicion level should be maintained for patients presenting with infertility, repeated pregnancy loss, malpresentations, and a poor obstetric history. Early diagnosis and treatment will give better outcome among the cases who had recurrent abortions and infertility.

References

Antaratani RC, Kumar S, Raju V. Study of mullerian anomalies over 5 years in a tertiary care centre. Int J Reprod Contracept Obstet Gynecol. 2020;9(3):1083-8.

Vyas RC, Moghariya AM, Shah SR, Parikh PM, Shelat PM. Mullerian ductal anomalies and its outcome. Int J Reprod Contracept Obstet Gynecol. 2019;8(2):440-4.

Naeh A, Sigal E, Barda S, Hallak M, Gabbay-Benziv R. The association between congenital uterine anomalies and perinataloutcomes - does type of defect matters? J Matern Fetal Neonatal Med. 2022;35(25):7406-11.

Koranne P, Zele M, Wahane A. A study of obstetrics outcome in cases of uterine anomalies. MedPulse Int J Gynaecol. 2019;11(3):126-9.

Kabadi YM, Ayyanar A. A “cluster” of ten uterine anomalies observed in a single center over a short period of 4 weeks: a case series. J Med Case Reports. 2022;16(1):130.

Saravelos SH, Cocksedge KA, Li TC. Prevalence and diagnosis of congenital uterine anomalies in women with reproductive failure: A critical appraisal. Hum Reprod Update. 2008;14(5):415‑29.

Rackow BW, Arici A. Reproductive performance of women with mullerian anomalies. Curr Opin Obstet Gynecol. 2007;19(3):229-37.

Jayashree A, Kumar PU, Padmaja V, Vinodini L, Rani KS. An analysis of the role of uterine malformations in primary infertility- An observational study. Int J Curr Res Rev. 2015;7(16):62-7.

Sayed SA, Ouies SM, Elsayed BZ. Prevalence of congenital anomalies of uterus in Sohag Government: A descriptive study by trans vaginal three dimensional ultrasound. Med J Cairo Univ. 2019;87(December):4645-50.

Reyes Munoz E, Vitale SG, Alvarado Rosales D, Iyune Cojab E, Vitagliano A, Lohmeyer FM, et al. Müllerian anomalies prevalence diagnosed by hysteroscopy and laparoscopy in Mexican infertile women: Results from a cohort study. Diagnostics. 2019;9(4):149:1-7.

Joshi B, Kaushal A, Suri V, Gainder S, Choudhary N, Jamwal S, et al. Prevalence and pregnancy outcome of mullerian anomalies in infertile women: A retrospective study. J Hum Reprod Sci. 2021;14(4):431-5.

Rao BB, Tilloo SJ, Bawa M, Kinge A. Maternal and fetal outcome in Mullerian anomaly: A study at Tertiary care center in Northern Part of Maharashtra. Ind J Maternal-Fet Neonat Medi. 2017;4(1):23-8.

Al-Attar RMT, Amin YK. Congenital anomalies of reproductive system among infertile women attending Dr. Khawer Center for Infertility and IVF in Maternity Teaching Hospital in Erbil city: A retrospective study. Zanco J Med Sci. 2019;23(3):368-74.

Nisha S, Singh K, Kumari S. Prevalence of Mullerian anomaly among infertile patients. Eur J Mol Clin Med. 2020;7(10):3870-5.

Nagarathnamma R, James T, Prasad N. Pregnancy outcome in uterine anomalies. J Medi Sci. 2017;3(1):31-3.

Hiersch L, Yeoshoua E, Miremberg H, Krissi H, Aviram A, YogeY, et al. The association between Mullerian anomalies and short-term pregnancy outcome. J Matern Fetal Neonatal Med. 2016;29(16):2573-8.

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Published

2024-10-28

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Original Research Articles