A rare association of cervical tuberculosis and primary infertility in a young nulligravida female

Ravi Sah; Akanksha Deshwali; Kripa Yadav; Shriya Rawat; Divya Reddy; Shalini Bose; Garvita Gulati; Parish Kamdi; Vanshika Asati; Manisha Perka; Shashi Sah

doi:10.18203/2320-1770.ijrcog20242515

Authors

Ravi Sah Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Akanksha Deshwali Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Kripa Yadav Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Shriya Rawat Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Divya Reddy Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Shalini Bose Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Garvita Gulati Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Parish Kamdi Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Vanshika Asati Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Manisha Perka Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Shashi Sah Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20242515

Keywords:

Tuberculosis, Infertility, Ectocervix, Cervical carcinoma, Anti-tubercular therapy

Abstract

Tuberculosis of the cervix is rare and may have a clinical presentation and hypertrophic growth like morphological appearance masquerading as that of cervical carcinoma. Due to nonspecific symptoms, there is often a delay in diagnosis and treatment, and thereby increasing the risk of infertility in young females. Here, we present a rare case of a 26 years young female with primary infertility and cervical tuberculosis. The patient presented with complaints of being keen to conceive for 3 years and occasional post coital spotting p/v. Her ultrasonography (USG) pelvis and hormonal analysis and her husband’s semen analysis reports were normal. On per-speculum examination, the ectocervix was replaced by a friable growth that bled on touch. A biopsy of the growth was taken and sent for tuberculosis (TB), cartridge based nucleic acid amplification test (CBNAAT), and histopathology. Her CBNAAT was negative, but her histopathology showed numerous epithelioid cell granulomas along with Langhans giant cells and scant central necrosis, suggestive of tuberculosis of the cervix. The patient was sent to a TB clinic and was prescribed anti-tubercular therapy for 6 months. Thus, in any case of infertility in a young female with cervical growth mimicking cervical carcinoma, a differential diagnosis should always be kept in mind.

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