Study of perinatal outcome in human immunodeficiency virus positive women

Shiva Gautam, Tushar Shah


Background: HIV remained a major public health problem in developing countries like India. Young adults especially women of reproductive age group are mainly affected. HIV is caused by human immune deficiency virus which decreases host immunity and leads to opportunistic infections. The aim of this study is to know the perinatal outcome of HIV positive women and the complications occurring in perinatal period leading to mortality.

Methods: It is a retrospective study done for 2 years from September 2013 to September 2015. Data was collected from PPTCT centre civil hospital Ahmedabad retrospectively from records only. Identity of patients was not disclosed.

Results: Among total 65 patients who were followed up 82.53% new-born were healthy and 10.99%were having morbidity factors. Causes of morbidity were low birth weight, IUGR, septicemia, jaundice etc. Hypoxemic ischemic encephalopathy is the most common cause of neonatal mortality and septicemia being second.

Conclusions: Maximum new-born were healthy. Hypoxic ischemic encephalopathy is the leading cause of neonatal death. Because of newer WHO guidelines of starting ART to all antenatal women, improved PPTCT counseling and better NICU facility neonatal outcome has improved.


HIV, NICU, WHO, Immune

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Ezechi OC, Gab Okafor CV, Oladele DA, Kalejaiye OO, Oke BO, Ohowodo HO, et al. Pregnancy, obstetric and neonatal outcomes in HIV positive Nigerian women. Afr J Reprod Health. 2013;17(3):160-8.

Prevalance of HIV infection in antenatal women according to NACO technical estimate report Available at

Sexually transmitted diseases; Cunnighams FG, Levono KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY eds, Williams’s obstetrics 23rd edition McGraw Hill; 2010:1246-1247.

Sexually transmitted diseases; Cunnighams FG, Levono KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY, Williams’s obstetrics 23rd edition McGraw Hill; 2010:1248.

HIV in pregnancy. Available at

Centre for disease control and prevention and association of public health laboratories. Laboratory testing for the diagnosis of HIV infection: updated recommendations, 2014. Available at

Guidelines for breastfeeding in HIV positive women Available at