Rising trends of peripartum cardiomyopathy: insights from the COVID-19 pandemic

Arshia Syed; Sohail M. Balbatti

doi:10.18203/2320-1770.ijrcog20252753

Authors

Arshia Syed Department of Obstetrics and Gynaecology, Al Ameen Medical College Hospital, Vijayapura, Karnataka, India
Sohail M. Balbatti Department of Respiratory Medicine, Al Ameen Medical College Hospital, Vijayapura, Karnataka, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20252753

Keywords:

Peripartum cardiomyopathy, COVID-19, LV dysfunction, High risk pregnancy

Abstract

Peripartum cardiomyopathy (PPCM) is a rare, life-threatening condition of unknown etiology occurring in late pregnancy or early postpartum. The COVID-19 pandemic has introduced new diagnostic challenges, particularly in distinguishing PPCM from COVID-19-related cardiomyopathy, both of which may share overlapping clinical features. This study was done to investigate the temporal relationship between SARS-CoV-2 infection and the onset of PPCM, highlighting possible implications for maternal health in the post-COVID-19 era. A prospective observational case series was conducted at a tertiary care center in South India. Four postpartum women with recent or past COVID-19 infection were diagnosed with PPCM over a six-month period. Three of the four patients succumbed despite intensive care and multidisciplinary interventions. The clustering of these cases in a short time frame and their shared history of COVID-19 infection raises questions regarding a potential pathogenic link. Future studies are needed to elucidate the pathophysiological mechanisms linking COVID-19 and PPCM.

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