Effectiveness of the OZiva® plant-based HerBalance supplement in the management of polycystic ovary syndrome: a real-world evidence study

Ratna Upadhyay; Mihir C. Gadani; Nikita S. Tendulkar

doi:10.18203/2320-1770.ijrcog20242794

Authors

Ratna Upadhyay Zywie Venture Pvt Ltd, Andheri East, Mumbai, Maharashtra, India
Mihir C. Gadani Zywie Venture Pvt Ltd, Andheri East, Mumbai, Maharashtra, India
Nikita S. Tendulkar Zywie Venture Pvt Ltd, Andheri East, Mumbai, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20242794

Keywords:

Infertility, Menstrual cycle, Polycystic ovary syndrome, Hyperandrogenism, Patient reported outcomes

Abstract

Background: Polycystic ovary syndrome (PCOS) is a complex heterogeneous endocrine disorder that is characterized by polycystic ovaries, chronic anovulation, and hyperandrogenism. We evaluated the efficacy and safety of OZiva® Plant Based HerBalance for PCOS (HBPCOS) supplement therapy on females suffering from symptoms and signs of PCOS.

Methods: This study employed a retrospective, questionnaire-based design to gather real-world evidence. A total of 153 female participants between the age range of 20-50 years diagnosed with PCOS or related symptoms were enrolled in this study. Primary data was collected using an electronic diary, capturing demographic characteristics and pre- treatment and post-treatment statuses of PCOS clinical signs and symptoms.

Results: In this, Female participants, with an average age of 28.70 ± 5.34 years. years and a history of PCOS for an average duration of 3 months, were recruited. Of the female participants, >87% of those with menstrual cramps, >92% with menstrual bleeding issues, 80% with acne, 64% with excess facial hair, 74% with weight management issues, 61% with difficulty conceiving, and >68% with irregular menses experienced complete or partial resolution of their symptoms after three months of consuming OZiva® HBPCOS. There was a statistically significant improvement in symptoms across the participants.

Conclusion: This study shows that PCOS-related infertility, obesity/difficulty managing weight, menstrual issues, and dermatological symptoms/signs have been significantly reduced after consuming OZiva® HBPCOS product for 3 months.

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