Primary uterine rhabdomyosarcoma: a unique presentation

Ishaan Sachin Padore; Archna Sachin Padore; Rahi R. Shetye; Vedha R. Shetye; Sachin S. Padore

doi:10.18203/2320-1770.ijrcog20243214

Authors

Ishaan Sachin Padore Padore Clinic Shivanjali, Kokate Alli, Pashan Gaon, Pashan, Pune, Maharashtra, India
Archna Sachin Padore Padore Clinic Shivanjali, Kokate Alli, Pashan Gaon, Pashan, Pune, Maharashtra, India
Rahi R. Shetye Goa Medical College, Bambolim, Goa, India
Vedha R. Shetye Goa Medical College, Bambolim, Goa, India
Sachin S. Padore Padore Clinic Shivanjali, Kokate Alli, Pashan Gaon, Pashan, Pune, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20243214

Keywords:

Uterine rhabdomyosarcoma, Immunohistocytochemistry, MRI

Abstract

Uterine rhabdomyosarcoma in adults is extremely rare. We present the case of a 61-year-old P1L1 postmenopausal female who came with abdominal distension and pedal edema since, 20 days. The typical presentation of post-menopausal bleeding was absent in this patient. The clinical presentation, massively raised CA 125 levels and CT findings pointed towards an ovarian malignancy. USG and MRI leaned towards carcinoma endometrium. The final diagnosis was clinched on immunohistochemical studies. The tumor had an aggressive course with a fatal outcome within days.

Metrics

Metrics Loading ...

References

V. Raney RB, Anderson JR, Barr FG. Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for intergroup rhabdomyosarcoma study. J Pediatr Hematol Oncol. 2001;23:215-20.

Ferguson SE, Gerald W, Barakat RR, Chi DS, Soslow RA. Clinicopathologic features of rhabdomyosarcoma of gynaecologic origin in adults. Am J Surg Pathol. 2007;31:382-9.

Pinto A, Kahn RM, Rosenberg AE, Slomovitz B, Quick CM, Whisman MK, et al. Uterine rhabdomyosarcoma in adults.. Hum Pathol. 2018;74:122-8.

Gerber NK, Wexler LH, Singer S. Adult rhabdomyosarcoma survival improved with treatment on multimodality protocols. Int J Radiat Oncol Biol Phys. 2013;86:58–63.

Hawkins WG, Hoos A, Antonescu CR. Clinicopathologic analysis of patients with adult rhabdomyosarcoma. Cancer. 2001;91:794-803.

Toro JR, Travis LB, Wu HJ, Zhu K, Fletcher CD, Devesa SS. Incidence patterns of soft tissue sarcomas, regardless of primary site, in the surveillance, epidemiology and end results program, 1978-2001: an analysis of 26,758. Int J Cancer. 2006;119:2922-30.

Arndt CA, Donaldson SS, Anderson JR. What constitutes optimal therapy for patients with rhabdomyosarcoma of the female genital tract?. Cancer. 2001;91:2454-68.

Ferrari A, Dileo P, Casanova M. Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer. 2003;98:571-80.

Little DJ, Ballo MT, Zagars GK. Adult rhabdomyosarcoma: outcome following multimodality treatment. Cancer. 2002;95:377-88.