Epidemiological profile of women with endometriosis: a study in a tertiary care hospital in Bangladesh

Authors

  • Sabrin Farhad Department of Obstetrics and Gynecology, Uttara Adhunik Medical College Hospital (UAMCH), Dhaka, Bangladesh
  • M. Roknuzzman Department of Surgery, Uttara Adhunik Medical College Hospital (UAMCH), Dhaka, Bangladesh
  • Afroza Akhtar Department of Obstetrics and Gynecology, Zainul Haque Sikder Women's Medical College and Hospital Dhaka, Bangladesh

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20243576

Keywords:

Epidemiological profile, Endometriosis, Ovarian cysts, Pelvic pain, Women

Abstract

Background: Endometriosis is a chronic and often painful condition characterized by the growth of tissue similar to the endometrium (the lining inside the uterus) outside the uterus. It primarily affects women of reproductive age and is a leading cause of pelvic pain and infertility. This study aimed to assess the epidemiological profile of women with endometriosis.

Methods: This prospective observational study was conducted in the Department of Obstetrics and Gynecology, Uttara Adhunik Medical College Hospital, Dhaka, Bangladesh from January 2022 to December 2022. As the study subjects, a total of 113 women with a confirmed surgical diagnosis of endometriosis enrolled in this study purposively. A purposive sampling technique was used in sample selection. Data were analyzed by MS Office tools.

Results: The mean age of respondents was 32.1±5.2 years, 69% were housewives and 58% were married. Main complaints included cyclic pelvic pain (42.5%), acyclic pelvic pain (23.9%), heavy menstrual bleeding (14.2%), amenorrhea (4.4%) and palpable mass (6.2%). Premenstrual syndrome was observed in 72% of cases and 46% of participants were infertile. Investigations revealed 82.3% had ovarian cysts, 47.8% experienced dysmenorrhea and 31.9% suffered from primary infertility. Deeply infiltrating endometriosis was prevalent in 60.2%, 57.5% were in Stage-III/IV and 42.5% were in Stage-I/II.

Conclusions: Endometriosis is most prevalent among younger married housewives. Main complaints include cyclic/acyclic pelvic pain, heavy menstrual bleeding, amenorrhea and palpable mass. Premenstrual syndrome and ovarian cysts are very common, while deeply infiltrating endometriosis being the most prevalent among endometriosis patients.

Metrics

Metrics Loading ...

References

Ballweg ML. Treating endometriosis in adolescents: does it matter? J Pediatr Adolesc Gynecol. 2011;24(5):2-6.

Janssen EB, Rijkers AC, Hoppenbrouwers K, Meuleman C, D'Hooghe TM. Prevalence of endometriosis diagnosed by laparoscopy in adolescents with dysmenorrhea or chronic pelvic pain: a systematic review. Hum Reprod. 2013;19:570-82.

Oliveira, FR, Dela Cruz C, Del Puerto HL. Stem Cells: Are They the Answer to the Puzzling Etiology of Endometriosis? Histo Histopathol. 2012;27:23-9.

Vanina NAM, Abega A, Serge N. Epidemiological Profile and Location of Lesions According to #ENZIAN of Patients Operated on for Endometriosis in a Public Endoscopic Surgery Centre, Yaounde, Cameroon. Open J Obst and Gynecol. 2012;13:1919-27.

Hughes CL, Foster WG, Agarwal SK, Mettler L. The Impact of Endometriosis on the Health of Women. Biomed Res Int. 2015;3:65951.

Koltermann KC, Schlotmann A, Schröder H, Willich SN, Reinhold T. Economic burden of deep infiltrating endometriosis of the bowel and the bladder in Germany: The statutory health insurance perspective. Z Evid Fortbild Qual Gesundhwes. 2016;118-119:24-30.

Zondervan KT, Becker CM, Missmer SA. Endometriosis. N Engl J Med. 2020;382(13):1244-56.

Cardoso, Jéssica Vilarinho. "Perfil epidemiológico de mulheres com endometriose: um estudo descritivo retrospectivo." Revista Brasileira de Saúde Materno Infantil. 20 (2021):1057-67.

Riccio LDGC, Santulli P, Marcellin L, Abrão MS, Batteux F, Chapron C. Immunology of endometriosis. Best Pract Res Clin Obstet Gynaecol. 2018;50:39-49.

Ferrero S, Remorgida V, Maganza C, Venturini PL, Salvatore S, Papaleo E, et al. Aromatase and endometriosis: estrogens play a role. Ann N Y Acad Sci. 2014;1317:17-23.

Cardoso JV, Abrão MS, Vianna-Jorge R, Ferrari R, Berardo PT, Machado DE, Perini JA. Combined effect of vascular endothelial growth factor and itsreceptor polymorphisms in endometriosis: a case-control study. Eur J Obstet Gynecol Reprod Biol. 2017;209:25-33.

Chapron C, Lang JH, Leng JH, Zhou Y, Zhang X, Xue M, et al. Factors and regional differences associated with endometriosis: a multi- country, case-control study. Adv Ther. 2016;33(8):1385- 407.

Backonja U, Hediger ML, Chen Z, Lauver DR, Sun L, Peterson CM, et al. Beyond Body Mass Index: Using Anthropometric Measures and Body Composition Indicators to Assess Odds of an Endometriosis Diagnosis. J Womens Health (Larchmt). 2017;26(9): 941-50.

Calhaz-Jorge C, Mol BW, Nunes J, Costa AP. Clinical predictive factors for endometriosis in a Portuguese infer- tile population. Hum Reprod. 2004;19(9):2126-31.

Heilier JF, Donnez J, Nackers F, Rousseau R, Verougstraete V, Rosenkranz K, et al. Environmental and host-associated risk factors in endometriosis and deep endometriotic nodules: a matched case-control study. Environ Res. 2007;103(1):121-9.

Prescott J, Farland LV, Tobias DK, Gaskins AJ, Spiegelman D, J.E. Chavarro, et al. A prospective cohort study of endometriosis and subsequent risk of infertility. Hum Reprod. 2016;31(7):1475-82.

Peterson CM, Johnstone EB, Hammoud AO, Stanford JB, Varner MW, Kennedy A, et al. Risk factors associated with endometriosis: importance of study population for characterizing disease in the ENDO Study. Am J Obstet Gynecol. 2013;208(6):1-11.

Eisenberg VH, Weil C, Chodick G, Shalev V. Epidemiology of endometriosis: a large population-based database study from a healthcare provider with 2 million members. An Int J Gynaecol Obstet. 2018;125(1):55-62.

Audebert A, Lecointre L, Afors K, Koch A, Wattiez A, Akladios C. Adolescent Endometriosis: Report of a Series of 55 Cases with a Focus on Clinical Presentation and Long-Term Issues. J Minim Invasive Gynecol. 2015;22(5):834-40.

Liu X, Long Q, Guo SW. Surgical History and the Risk of Endometriosis: A Hospital-Based Case-Control Study. Reprod Sci. 2016;23(9):1217-24.

Moradi M, Parker M, Sneddon A, Lopez V, Ellwood D. Impact of endometriosis on women's lives: a qualitative study. BMC Women’s Health. 2014;14:123.

Sinaii N, Plumb K, Cotton L, Lambert A, Kennedy S, Zondervan K, et al. Differences in characteristics among 1,000 women with endometriosis based on extent of disease. Fertil Steril. 2008;89(3):538-45.

Pandian Z, Akande VA, Harrild K, Bhattacharya S. Surgery for tubal infertility. Cochrane Database Syst Rev. 2008;(3):6415.

Briceag I, Costache A, Purcarea VL, Cergan R, Dumitru M, Briceag I, et al. Fallopian tubes--literature review of anatomy and etiology in female infertility. J Med Life. 2015;8(2):129-31.

Pereira N, Kligman I. Clinical implications of accessory fallopian tube ostium in endometriosis and primary infertility. Womens Health (Lond). 2016;12(4):404-6.

Downloads

Published

2024-11-28

Issue

Section

Original Research Articles