Fetomaternal outcome in pregnancy with diabetes mellitus
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20243190Keywords:
Diabetes mellitus, Gestational, Maternal, Fetomaternal outcomeAbstract
Background: South Asian population has more prevalence of diabetes mellitus in pregnancy which can impact both mother and foetus and can also increase the risk of future diabetes.
Methods: Seventy pregnant women hospitalised at SVP from August 2021 to May 2024 for diabetes mellitus during pregnancy were the subjects of the current ambisprective cohort research.
Results: There were 45 women (64.28%) with gestational diabetes mellitus and 25 women (35.72%) with overt diabetes among the 70 women who were reported. The following complications were seen in the pregnant women in this study: 24 cases of polyhydramnios (34.28% of the total), 18 cases of macrosomia in the foetus (25.7%), 1 case of foetal cardiac abnormality (1.4%), and 40 cases of caesarean section (57.15% of the total).
Conclusions: In order to attain positive fetomaternal outcomes, preventive medicine should prioritise the early screening and diagnosis of diabetes during pregnancy, as this condition has negative consequences on the mother and the unborn child.
References
American Diabetes Association. Standards of medical care in diabetes- 2010. Diabetes Care. 2010;33(Supplement_1): S11-61.
Dornhorst A, Paterson CM, Nicholls JS, Wadsworth J, Chiu DC, Elkeles RS, et al. High prevalence of gestational diabetes in women from ethnic minority groups. Diabetic Med. 1992;9(9):820-5.
Aberg A, Westbom L, Källén B. Congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes. Early Hum Dev. 2001;61(2):85-95.
Tripathi R, Verma D, Gupta VK, Tyagi S, Kalaivani M, Ramji S, et al. Evaluation of 75 gm glucose load in non-fasting state [diabetes in pregnancy study group of India (DIPSI) criteria] as a diagnostic test for gestational diabetes mellitus. Indian J Med Res. 2017;145(2):209-14.
Nanda S, Savvidou M, Syngelaki A, Akolekar R, Nicolaides KH. Prediction of gestational diabetes mellitus by maternal factors and biomarkers at 11 to 13 weeks. Prenat Diagn. 2011;31(2):135-41.
Bhandari J, Thada PK, Khattar D. Diabetic Embryopathy. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024.
Shefali AK, Kavitha M, Deepa R, Mohan V. Pregnancy outcomes in pre-gestational and gestational diabetic women in comparison to non-diabetic women- a prospective study in Asian Indian mothers (CURES-35). J Assoc Phys India. 2006;54:613-8.
Saxena P, Tyagi S, Prakash A, Nigam A, Trivedi SS. Pregnancy outcome of women with gestational diabetes in a tertiary level hospital of north India. Indian J Community Med. 2011;36(2):120-3.
Dudhwadkar AR, Fonseca MN. Maternal and fetal outcome in gestational diabetes mellitus. Int J Reprod Contracept Obstet Gynecol. 2016;5:3317-21.
Muche AA, Olayemi OO, Gete YK. Effects of gestational diabetes mellitus on risk of adverse maternal outcomes: a prospective cohort study in Northwest Ethiopia. BMC Pregnancy Childbirth. 2020;20(1):73.
Bhat M, Ramesha KN, Sarma SP, Menon S, Sowmini CV. Determinants of gestational diabetes mellitus: a case control study in a district tertiary care hospital in south India. Int J Diabetes Developing Countries. 2010;30(2):91.
Hobbins JC. Ultrasound in the management of the diabetic pregnancy. In: Reece EA, Couston DR (eds). Diabetes Mellitus in Pregnancy: Principles and Practice. Churchill Livingstone: New York, NY; 1988:347-362.
Mazor M, Ghezzi F, Maymon E, Shoham-Vardi I, Vardi H, Hershkowitz R, et al. Polyhydramnios is an independent risk factor for prenatal mortality and intrapartum morbidity in preterm delivery. Eur J Gynecol Reprod Biol 1996;70:41-7.
Kale SD, Yajnik CS, Kulkarni SR, Meenakumari K, Joglekar AA, Khorsand N, et al. High risk of diabetes and metabolic syndrome in Indian women with gestational diabetes mellitus. Diabetic Med. 2004;21(11):1257-8.