Cytopathological pattern of cervical Papanicolaou smear in women of reproductive age group
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20243586Keywords:
Carcinoma cervix, PAP smear, Cervical biopsyAbstract
Background: Cervical is the most prevalent genital cancer, the second most frequent gynaecological cancer, and the second-highest rate of cancer-related death among Indian women. Cervical cancer is preventable because it has a prolonged preinvasive stage, effective cervical screening programs exist, and preinvasive lesions that can be treated.
Methods: The prospective observational study has been carried out on all women attending the (OBGY) OPD in GSVM medical college and hospital. 1000 women were selected for the study. Appropriate history was taken and the women were advised to undergo Papanicolaou (PAP) smear and were followed for reports and were further treated accordingly.
Results: As the number of risk factors increased, the higher the degree of lesions were observed in cervix. After being counselled for screening, 100% women agreed for PAP smear in which 71.5% of the women had normal results, 10.5% were diagnosed with cervicitis, 9.3% had vaginitis, 3.2% had an inadequate smear, 2.1% also had an inadequate smear, 1.3% had bacterial vaginosis, 1.0% had ASCUS, 0.8% had HSIL, and 0.3% showed reactive cellular changes. Following a cervical biopsy, 14.9% of the women in need of additional testing had a normal biopsy, and 24.3% had chronic cervicitis. Invasive carcinomas affected 16.2% CIN1, 2.7% CIN2, 1.4% CIN3, and 1.4% of CIN1. 10.8% of the individuals could not be reached for follow-up.
Conclusions: In our study we found that after counselling 100% women agreed for PAP smear and hence this shows that counselling is very important to create awareness regarding prevention of cancer. Multiple risk factors are associated with cervical cancer and awareness regarding it is necessary in general population to reduce the risk of cervical cancer.
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References
Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, et al. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Global Health. 2020;8(2):e191-203.
Arulogun OS, Maxwell OO. Perception and utilization of cervical cancer screening services among female nurses in University College Hospital, Ibadan, Nigeria. Pan Afr Med J. 2012;11:69.
NHS Cervical Screening Programme, Cervical screening a pocket guide. Available at: http://www.cancerscreening.nhs.uk/cervical/publications/cervicalpocket2009.pdf. Accessed on September 15 2024.
Kavanagh K, Pollock KG, Cuschieri K, Palmer T, Cameron RL, Watt C, et al. Changes in the prevalence of human papillomavirus following a national bivalent human papillomavirus vaccination programme in Scotland: A 7-year cross-sectional study. The Lancet Infectious Dis. 2017;17(12):1293-302.
Chatterjee A. The next generation of HPV vaccines: Nonvalent vaccine V503 on the horizon. Expert Rev Vaccines. 2014;13(11):1279-90.
Nour NM. Cervical cancer: a preventable death. Rev Obstet Gynecol. 2009;2:240-4.
Miller AB, Nazeer S, Fonn S, Brandup-Lukanow A, Rehman R, Cronje H, et al. Report on consensus conference on cervical cancer screening and management. Int J Cancer. 2000;86:440-7.
Raychaudhuri S, Mandal S. Socio-demographic and behavioural risk factors for cervical cancer and knowledge, attitude and practice in rural and urban areas of North Bengal, India. Asian Pac J Cancer Prev. 2012;13(4):1093-6.
Ahuja R, Sharma P, Chawla R. Pap smear in antenatal women: a valuable opportunity for screening and awareness. Int J Res Med Sci. 2020;8(4):1213-6.
Agrawal S, Agrawal S, Gupta P. Study of cervical cytology in pap smears in a tertiary care hospital of North Maharashtra. Int J Reprod Contracept Obstet Gynecol. 2023;12(7):2185-91.
Gupta P, Faruqi M, Chandra S, Shah S, Kulshrestha R. The correlation between colposcopy, cervical cytology and histopathology in the diagnosis and management of cervical lesions: a cross sectional study Int J Reprod Contracept Obstet Gynecol. 2020;9(7):2729-35.