Expectant versus active management of small for gestational age pregnancies with normal Doppler parameters: an observational study
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20243948Keywords:
Expectant management, Normal Doppler parameters, Small for gestational age pregnancyAbstract
Background: A successful pregnancy depends on the foetus developing normally, which in turn impacts the foetal health in future. While 70% of small for gestational age (SGA) babies are naturally small and safe, 30% are abnormally little and have a lesser kind of fetal growth restriction (FGR) when their Doppler measurements are normal. Despite normal Doppler at 37 weeks, clinicians often induce all SGA pregnancies, which increases the risk of iatrogenic preterm delivery and surgical treatments. The aim of this study was to assess pregnancy outcome of expectant and active management of small for gestational age pregnancies with normal Doppler parameters.
Methods: Study included pregnant women diagnosed as small for gestational age pregnancy with normal Doppler parameters between 28 and 39weeks. The study population (n=60) were divided into two groups- Group 1- Expectant management: To wait up to 39weeks for spontaneous onset of labor, if not induction at 39 weeks. Group 2 - Active management: Induction of labor at 37weeks of gestation. All study participants were followed until delivery. Maternal parameters like onset of labour, Mode of delivery were studied, fetal and neonatal parameters like Apgar score, birth weight and NICU admission were studied.
Results: Group 1 expectantly managed group had more spontaneous onset of labour compared to Group 2 which was statistically significant and higher birth weight, more vaginal deliveries and lesser NICU admissions were noted in group 1 compared to group 2.
Conclusions: We concluded that SGA pregnancies with normal Doppler parameters may be considered for elective induction at a later date for better maternal and fetal outcomes.
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References
Figueras F, Gratacos E. An integrated approach to fetal growth restriction. Best Pract Res Clin Obstet Gynaecol. 2017;38:48-58.
Maulik D. Fetal growth restriction: the etiology. Clin Obstet Gynecol. 2006;49(2):228-35.
McCowan L, Horgan RP. Risk factors for small for gestational age infants. Best Pract Res Clin Obstet Gynaecol. 2009;23(6):779-93.
Kramer MS. Determinants of low birth weight: methodological assessment and meta analysis. Bull World Health Organ. 1987;65(5):663-737.
Osuchukwu OO, Reed DJ. Small for Gestational Age. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024.
Bond DM, Gordon A, Hyett J, de Vries B, Carberry AE, Morris J. Planned early delivery versus expectant management of the term suspected compromised baby for improving outcomes. Cochrane Database Syst Rev. 2015;2015(11):CD009433.
National Womens Health. Small for Gestational Age and Fetal Growth Restriction from 34 weeks - Detection and Management. https://www.nationalwomenshealth.adhb.govt.nz/assets/Womens-health/Documents/Policies-and-guidelines. Accessed 01 May 2024.
Hidaka N, Sato Y, Kido S, Fujita Y, Kato K. Expectant management of pregnancies complicated by fetal growth restriction without any evidence of placental dysfunction at term: Comparison with routine labor induction. J Obstet Gynaecol Res. 201;44(1):93-101.
Boers KE, Bijlenga D, Mol BWJ, LeCessie S, Birnie E, van Pampus MG, et al. Disproportionate intrauterine growth intervention trial at term: DIGITAT. BMC Pregnancy Childbirth. 2007;7:12.
Bukowski R, Hansen NI, Willinger M, Reddy UM, Parker CB, Pinar H, et al. Fetal growth and risk of stillbirth: a population-based case-control study. PLoS Med. 2014;11(4):e1001633.
Royal College of Obstetricians and Gynaecologists. Small-for-gestational-age fetus and a growth restricted fetus, investigation and care (green-top guideline No. 31). Available at: https://www.rcog.org.uk/guidance/browse-all-guidance/green-top-guidelines/small-for-gestational-age-fetus-and-a-growth-restricted-fetus-investigation-and-care-green-top-guideline-no-31/. Accessed 01 May 2024.
Boers KE, Vijgen SMC, Bijlenga D, van der Post JM, Bekedam DJ, Kwee A, et al. Induction versus expectant monitoring for intrauterine growth restriction at term: randomised equivalence trial (DIGITAT). BMJ. 2010;341:c7087.
Sengupta S, Carrion V, Shelton J, Wynn RJ, Ryan RM, Singhal K, et al. Adverse neonatal outcomes associated with early-term birth. JAMA Pediatr. 2013;167(11):1053-9.