Primary extragastrointestinal stromal tumor of greater omentum misdiagnosed as an adnexal tumor: a case report
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20250542Keywords:
Extragastrointestinal stromal tumor, Greater omentum, Oncology, SurgeryAbstract
Gastrointestinal stromal tumors (GISTs) are the most frequently occurring mesenchymal tumors in the gastrointestinal system. These tumors are believed to arise from interstitial cells of Cajal, the gastrointestinal pacemaker cells, due to the presence of tyrosine kinase receptors in their tissue. When tumors with similar morphological and immunohistochemical properties are found outside the gastrointestinal tract such as the mesentery, retroperitoneum, and every now and then the omentum, they are classified as extragastrointestinal stromal tumors (EGISTs). We report a case of a primary epithelioid (EGIST) of the greater omentum, the tumor was diagnosed in women with non-specific symptoms who presented for abdominal pain initially misdiagnosed as an adnexal tumor. This report highlights the need to consider EGIST in the differential diagnosis of abdominal and pelvic tumors and underscores the importance of EGIST-specific studies to evaluate treatment modalities for improved oncological outcomes and quality of life.
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References
Kataoka M, Saitoh T, Kawashima K, Yazaki T, Sonoyama H, Okimoto E, et al. Primary Extragastrointestinal Stromal Tumor of Greater Omentum with Intraperitoneal Bleeding. Intern Med. 2021;60(21):3413-9. DOI: https://doi.org/10.2169/internalmedicine.6519-20
Barros A, Linhares E, Valadão M, Gonçalves R, Vilhena B, Gil C, Ramos C. Extragastrointestinal stromal tumors (EGIST): a series of case reports. Hepatogastroenterology. 2011;58(107-108):865-8.
Franzini C, Alessandri L, Piscioli I, Donato S, Faraci R, Morelli L, et al. Extra-gastrointestinal stromal tumor of the greater omentum: report of a case and review of the literature. World J Surg Oncol. 2008;6:25. DOI: https://doi.org/10.1186/1477-7819-6-25
Toutounji Z, Alahmad Z, Attar M, Sarminy M, Alsado WM, Mohammad M. Unusual location of gastrointestinal stromal tumor (GIST): A case report and literature review of greater omentum location. Int J Surg Case Rep. 2024;119:109793. DOI: https://doi.org/10.1016/j.ijscr.2024.109793
Kadel D, Bhuju S, Thapa BR, Chalise S, Kumar Sah S. Curative intent treatment of late presented extragastrointestinal stromal tumor: two identical case reports with literature review. J Surg Case Rep. 2021;2021(6):rjab220. DOI: https://doi.org/10.1093/jscr/rjab220
Castillo-Sang M, Mancho S, Tsang AW, Gociman B, Almaroof B, Ahmed MY. A malignant omental extra-gastrointestinal stromal tumor on a young man: a case report and review of the literature. World J Surg Oncol. 2008;6:50. DOI: https://doi.org/10.1186/1477-7819-6-50
Laroia ST, Yadav T, Rastogi A, Sarin S. Malignant Retroperitoneal Extra-Gastrointestinal Stromal Tumor: A Unique Entity. World J Oncol. 2016;7(2-3):45-50. DOI: https://doi.org/10.14740/wjon926w
Wang Y, Liu Y, Zhong Y, Ji B. Malignant extra-gastrointestinal stromal tumor of the liver: A case report. Oncol Lett. 2016;11(6):3929-32. DOI: https://doi.org/10.3892/ol.2016.4531
Almeida M, Sousa F, Resende F, Devesa V, Ferrão A, Carneiro S, et al. Primary EGIST of the greater omentum - a rare presentation. Acta Chir Belg. 2024;124(2):137-42. DOI: https://doi.org/10.1080/00015458.2023.2201084
Koumarianou A, Economopoulou P, Katsaounis P, Laschos K, Arapantoni-Dadioti P, Martikos G, et al. Gastrointestinal stromal tumors (GIST): a prospective analysis and an update on biomarkers and current treatment concepts. Biomark Cancer. 2015;7(1):1-7. DOI: https://doi.org/10.4137/BIC.S25045