Abnormal uterine bleeding as first symptom of acute promyelocytic leukaemia: a case report and literature review

Authors

  • Love Chimezirim Okafor Department of Obstetrics and Gynaecology, The Limi Hospitals, Abuja, Nigeria
  • Ebelechukwu Adaobi Obi Department of Obstetrics and Gynaecology, The Limi Hospitals, Abuja, Nigeria
  • Chinenye Ukoha Department of Obstetrics and Gynaecology, The Limi Hospitals, Abuja, Nigeria
  • Aminyene Essien Meraiyebu Department of Radiology, The Limi Hospitals, Abuja, Nigeria
  • Kingsley Iyoko Iseko Department of Radiology, The Limi Hospitals, Abuja, Nigeria
  • Uchechi Nzerem Olua Department of Family Medicine, The Limi Hospitals, Abuja, Nigeria

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20251590

Keywords:

Uterine bleeding, Haematological cancer, Acute promyelocytic leukemia, Subarachnoid haemorrhage

Abstract

Abnormal uterine bleeding is common within gynaecology practice. It affects up to one-third of women during their lifetime. Hematological cancer is a rare form of coagulopathy leading to abnormal uterine bleeding. Uterine bleeding caused by coagulopathy as a complication of acute promyelocytic leukaemia can be fatal. The aim was to document a rare case of acute severe abnormal uterine bleeding as first symptom of haematological cancer (Acute Promyelocytic Leukaemia). She was a 45-year-old Para 2 woman who presented at the emergency room with chief complaint of uterine bleeding of six days duration. She also developed a throbbing headache that suddenly intensified, initially on the left side of her head, radiating to the periorbital area. Assessment of Acute promyelocytic Leukaemia complicated by Subarachnoid haemorrhage was made. She was referred to National Hospital Abuja for further management. Uterine bleeding caused by coagulopathy as a complication of acute promyelocytic leukaemia can be life threatening, hence early diagnosis and treatment is imperative.

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References

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Published

2025-05-29

How to Cite

Okafor, L. C., Obi, E. A., Ukoha, C., Meraiyebu, A. E., Iseko, K. I., & Olua, U. N. (2025). Abnormal uterine bleeding as first symptom of acute promyelocytic leukaemia: a case report and literature review. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 14(6), 1961–1964. https://doi.org/10.18203/2320-1770.ijrcog20251590

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Section

Case Reports