Successful management of a young patient with endometroid ovarian carcinoma with positive immuno-histochemistry

Chiranjeev Shetty; Meena Satia; V. Bhadhwar; Nilofer Yelurkar

doi:10.18203/2320-1770.ijrcog20251775

Authors

Chiranjeev Shetty Department of Obstetrics and Gynecology, Dr. D. Y. Patil Hospital Nerul, Navi Mumbai, Maharashtra, India
Meena Satia Department of Obstetrics and Gynecology, Dr. D. Y. Patil Hospital Nerul, Navi Mumbai, Maharashtra, India
V. Bhadhwar Department of Obstetrics and Gynecology, Dr. D. Y. Patil Hospital Nerul, Navi Mumbai, Maharashtra, India
Nilofer Yelurkar Department of Obstetrics and Gynecology, Dr. D. Y. Patil Hospital Nerul, Navi Mumbai, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20251775

Keywords:

Endometrioid ovarian carcinoma, Endometriosis-associated ovarian cancer, Immunohistochemistry, Estrogen receptor, Radiological evaluation, Staging laparotomy

Abstract

Ovarian cancer is overall a disease of postmenopausal women although, in about 12% of cases, it may develop during child bearing age. This estimate includes numerous women with borderline and non-epithelial tumours typically presenting during child bearing age group. Although there are several case reports of Endometriosis-associated ovarian cancer (EAOC) at a young age, the exact age distribution of EAOC diagnosis is still not well- expounded. Presenting here with a young patient with ovarian malignancy with positive immuno-histochemistry for both oestrogen and progesterone receptor.

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References

Kurman RJ, Shih IM. The dualistic model of ovarian carcinogenesis: revisited, revised, and expanded. American J Pathol. 2016;186(4):733-47. DOI: https://doi.org/10.1016/j.ajpath.2015.11.011

Richani D, Gilchrist RB. The epidermal growth factor network: role in oocyte growth, maturation and developmental competence. Human Reprod. 2018;24(1):1-4. DOI: https://doi.org/10.1093/humupd/dmx029

Saavalainen L, Lassus H, But A, Tiitinen A, Härkki P, Gissler M, et al. Risk of gynecologic cancer according to the type of endometriosis. Obst Gynecol. 2018;131(6):1095-102. DOI: https://doi.org/10.1097/AOG.0000000000002624

Wiegand KC, Shah SP, Al-Agha OM, Zhao Y, Tse K, Zeng T, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. New England J Med. 2010;363(16):1532-43. DOI: https://doi.org/10.1056/NEJMoa1008433

Westhoff GL, Chen Y, Teng NN. Targeting FOXM1 improves cytotoxicity of paclitaxel and cisplatinum in platinum-resistant ovarian cancer. International J Gynecol Cancer. 2017;27(8):1602-9. DOI: https://doi.org/10.1097/IGC.0000000000001063

Bigelow AM, Crane SS, Khoury FR, Clark JM. Catheter ablation of supraventricular tachycardia without fluoroscopy during pregnancy. Obst Gynecol. 2015;125(6):1338-41. DOI: https://doi.org/10.1097/AOG.0000000000000601

Kvaskoff M, Mahamat-Saleh Y, Farland LV, Shigesi N, Terry KL, Harris HR, et al. Endometriosis and cancer: a systematic review and meta-analysis. Human Reprod. 2021;27(2):393-420. DOI: https://doi.org/10.1093/humupd/dmaa045

Mikami Y. Endometriosis-related ovarian neoplasms: pathogenesis and histopathologic features. Diag Histopathol. 2014;20(9):357-63. DOI: https://doi.org/10.1016/j.mpdhp.2014.07.002

Li DP, Du C, Zhang ZM, Li GXBreastfeeding and ovarian cancer risk: a systematic review and meta-analysis of 40 epidemiological studies. Asian Pacific J Cancer Preven. 2014;15(12):4829-37. DOI: https://doi.org/10.7314/APJCP.2014.15.12.4829

Zhang X, Li M, Tang Z, Li X, Song T. Differentiation between endometriosis-associated ovarian cancers and non-endometriosis-associated ovarian cancers based on magnetic resonance imaging. Br J Radiol. 2021;94(1125):1441. DOI: https://doi.org/10.1259/bjr.20201441

Umeoka S, Koyama T, Togashi K, Kobayashi H, Akuta K. Vascular dilatation in the pelvis: identification with CT and MR imaging. Radiographics. 2004;24(1):193-208. DOI: https://doi.org/10.1148/rg.241035061

Love C, Tomas MB, Tronco GG, Palestro CJ. FDG PET of infection and inflammation. Radiographics. 2005;25(5):1357-68. DOI: https://doi.org/10.1148/rg.255045122

Zhu C, Xu Z, Zhang T, Qian L, Xiao W, Wei H, et al. Updates of pathogenesis, diagnostic and therapeutic perspectives for ovarian clear cell carcinoma. J Cancer. 2021;12(8):2295. DOI: https://doi.org/10.7150/jca.53395

Gong E, Pauly JM, Wintermark M, Zaharchuk G. Deep learning enables reduced gadolinium dose for contrast‐enhanced brain MRI. J Magn Reson Imag. 2018;48(2):330-40. DOI: https://doi.org/10.1002/jmri.25970

Gałczyński K, Chauvet P, Canis M, Bourdel N. Laparoscopic extraperitoneal lumboaortic lymphadenectomy in 10 steps–Let's make it easier. Gynecol Oncol. 2016;143(2):448-9. DOI: https://doi.org/10.1016/j.ygyno.2016.08.326

Medeiros LR, Rosa MI, Silva BR, Reis ME, Simon CS, Dondossola ER, da Cunha Filho JS. Accuracy of magnetic resonance in deeply infiltrating endometriosis: a systematic review and meta-analysis. Arch Gynecol Obst. 2015;291:611-21. DOI: https://doi.org/10.1007/s00404-014-3470-7