Study of ectopic pregnancy in a tertiary care hospital

Authors

  • Heny J. Patel Department of Obstetrics and Gynaecology, Smt. NHL MMC (SVPIMSR), Ahmedabad, Gujarat, India
  • Shashwat K. Jani Department of Obstetrics and Gynaecology, Smt. NHL MMC (SVPIMSR), Ahmedabad, Gujarat, India
  • Pushpa A. Yadava Department of Obstetrics and Gynaecology, Smt. NHL MMC (SVPIMSR), Ahmedabad, Gujarat, India
  • Rupa C. Vyas Department of Obstetrics and Gynaecology, Smt. NHL MMC (SVPIMSR), Ahmedabad, Gujarat, India
  • Nitya P. Asudani Department of Obstetrics and Gynaecology, Smt. NHL MMC (SVPIMSR), Ahmedabad, Gujarat, India
  • Naisargee G. Rawal Department of Obstetrics and Gynaecology, Smt. NHL MMC (SVPIMSR), Ahmedabad, Gujarat, India
  • Kashmira V. Dangar Department of Obstetrics and Gynaecology, Smt. NHL MMC (SVPIMSR), Ahmedabad, Gujarat, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20251238

Keywords:

Amenorrhea, Beta hCG, Ectopic pregnancy, Ultrasonography

Abstract

Background: Ectopic pregnancy, occurring in 1.5-2% of pregnancies globally, is a serious, life-threatening complication and a leading cause of maternal morbidity and mortality in the first trimester. It poses risks to the mother’s life and future fertility by causing potential damage to the fallopian tubes and ovaries.

Methods: This retrospective study was conducted at a tertiary care hospital in Ahmedabad, India, from February 2023 to January 2025, involving 40 women diagnosed with ectopic pregnancies. Detailed computerized patient records, including complaints, vital signs, demographics, medical history, and risk factors such as amenorrhea duration, pelvic pathology, surgeries, and infertility treatments, were analyzed. Ultrasound findings, urine pregnancy tests (UPT), and intraoperative observations were also recorded. Data were entered into a pre-structured proforma and analyzed using percentage-based methods.

Results: The majority of patients were aged 26-30 years, with 60% in their second pregnancy. Common risk factors included previous ectopic pregnancy (17.5%) and pelvic inflammatory disease (12.5%). Symptoms included amenorrhea (57.5%) and abdominal pain (60%). Among cases, 45% were ruptured tubal pregnancies, and 10% received methotrexate treatment.

Conclusions: Ectopic pregnancy should be considered in women of reproductive age with lower abdominal pain, regardless of amenorrhea or sterilization history. Early diagnosis through ultrasound and beta hCG tests is crucial to prevent maternal morbidity and mortality. Timely intervention can reduce complications and significantly improve outcomes.

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References

Walker JJ. Ectopic pregnancy. Clin Obstet Gynecol 2007;50(1):89-99. DOI: https://doi.org/10.1097/GRF.0b013e31802f4f79

Panti A, Ikechukwu NE, Luckman OO, Yakubu A, Egondu SC, Tanko BA. Ectopic pregnancy at Usmanu Danfodiyo University Teaching Hospital Sokoto: a tenyear review. Ann Niger Med. 2012;6(2):87-91. DOI: https://doi.org/10.4103/0331-3131.108128

Abdul FI. Ectopic pregnancy in Ilorin: a review of 278 cases. Niger J Med. 2000;9(3):92-6.

Attri P, Gupta A, Vij A, Gupta B. A clinical study of the incidence, management and outcome of ectopic pregnancy. Int J Clin Obstet Gynaecol. 2020;4(3):219-26. DOI: https://doi.org/10.33545/gynae.2020.v4.i3d.607

John A. Rock, Howard W. Jones III. Te Linde’s Operative Gynecology. 10th edition. Lippincott, Williams and Wilkins, a Wolters Kluwer business. USA. 2008;P798.

Weiss A, Beck-Fruchter R, Golan J, Lavee M, Geslevich Y, Shalev E. Ectopic pregnancy risk factors for ART patients undergoing the GnRH antagonist protocol: a retrospective study. Reprod Biol Endocrinol. 2016;14:1-8. DOI: https://doi.org/10.1186/s12958-016-0146-0

Gary Cunningham F, Leveno KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY. Williams Obstetrics. 23rd edition. McGraw-Hill Companies. USA. 2010;P238.

Houser M, Kandalaft N, Khati NJ. Ectopic pregnancy: a resident’s guide to imaging findings and diagnostic pitfalls. Emerg Radiol. 2022;29(1):161-72. DOI: https://doi.org/10.1007/s10140-021-01974-7

Lozeau AM, Potter B. Diagnosis and management of ectopic pregnancy. Am Fam Physician. 2005;72(9):1707-14.

Tahmina S, Daniel M, Solomon P. Clinical analysis of ectopic pregnancies in a tertiary care center in Southern India: a six-year retrospective study. J Clin Diagn Res. 2016;10(10):QC13. DOI: https://doi.org/10.7860/JCDR/2016/21925.8718

Majhi AK, Roy N, Karmakar KS, Banerjee PK. Ectopic Pregnancy-an analysis of 180 cases. J Indian Med Assoc. 2007;105(6):308-12.

Khaleeque F, Siddiqui RI, Jafarey SN. Ectopic pregnancies: a three-year study. J Pak Med Assoc. 2001;51(7):240-3.

Mullany K, Minneci M, Monjazeb R, C Coiado O. Overview of ectopic pregnancy diagnosis, management, and innovation. Womens Health (Lond). 2023;19:17455057231160349. DOI: https://doi.org/10.1177/17455057231160349

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Published

2025-04-28

How to Cite

Patel, H. J., Jani, S. K., Yadava, P. A., Vyas, R. C., Asudani, N. P., Rawal, N. G., & Dangar , K. V. (2025). Study of ectopic pregnancy in a tertiary care hospital. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 14(5), 1539–1543. https://doi.org/10.18203/2320-1770.ijrcog20251238

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Original Research Articles