Virilizing Leydig cell tumor of the ovary: from presentation to treatment - a case report

Authors

  • Kunthavvai Thanigachalam Department of Obstetrics and Gynecology, Chennai, Tamil Nadu, India
  • Mala Vijayakrishnan Department of Obstetrics and Gynecology, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20251600

Keywords:

Virilization, Leydig cell tumor, Androgen-secreting ovarian tumor, Hirsutism, Sex cord-stromal tumor

Abstract

Leydig cell ovarian tumor is a rare sex cord-gonadal stromal tumor which constitutes less than 0.2% of ovarian tumors. As they produce testosterone, virilization is the most common presenting feature. This case report discusses a multiparous, 55 years old, postmenopausal lady who presented with complaints of excessive scalp hair loss and increased facial hair growth since two years. On examination she had androgenic alopecia, increased facial and midline body hair and clitoromegaly. Blood investigations done showed elevated S. testosterone. CT abdomen done showed no pathological lesions in the adrenal glands. MRI done in view of suspicion of Androgen secreting ovarian tumour showed mildly enlarged left ovary measuring 2×1.8 cm with altered signal intensity. She underwent total laparoscopic hysterectomy with bilateral salpingo-oophorectomy. Post operatively, histopathological examination was reported as Benign Leydig cell tumour of left ovary.

 

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References

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Published

2025-05-29

How to Cite

Thanigachalam, K., & Vijayakrishnan, M. (2025). Virilizing Leydig cell tumor of the ovary: from presentation to treatment - a case report. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 14(6), 1996–1998. https://doi.org/10.18203/2320-1770.ijrcog20251600

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Section

Case Reports