Maternal-fetal obstetric outcomes in mothers of advanced maternal age: a cross-sectional analytical study at Saint-Joseph Hospital and the University Clinics of Kinshasa in the Democratic Republic of Congo

Antoine Tshimbundu Kayembe; Anne Kapinga Mutshiaudi; Alex Mutombo Baleka; Andy Mbangama Muela; Rahma Raschid Tozin; Roger Mbungu Mwimba; Dieudonné Sengeyi Mushengezi; Patrick Kahindo Muyayalo

doi:10.18203/2320-1770.ijrcog20251554

Authors

Antoine Tshimbundu Kayembe Department of Gynaecology and Obstetrics, Faculty of Medicine, University Notre-Dame of Kasayi, Central Kasaï, D. R. Congo https://orcid.org/0000-0003-2685-340X
Anne Kapinga Mutshiaudi Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Kinshasa, Kinshasa, D. R. Congo
Alex Mutombo Baleka Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Kinshasa, Kinshasa, D. R. Congo
Andy Mbangama Muela Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Kinshasa, Kinshasa, D. R. Congo https://orcid.org/0000-0003-2972-7708
Rahma Raschid Tozin Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Kinshasa, Kinshasa, D. R. Congo https://orcid.org/0000-0003-4767-9519
Roger Mbungu Mwimba Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Kinshasa, Kinshasa, D. R. Congo
Dieudonné Sengeyi Mushengezi Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Kinshasa, Kinshasa, D. R. Congo https://orcid.org/0000-0002-7197-8159
Patrick Kahindo Muyayalo Department of Gynaecology and Obstetrics, Faculty of Medicine, University of Kinshasa, Kinshasa, D. R. Congo https://orcid.org/0000-0001-7055-4138

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20251554

Keywords:

AMA, Obstetric outcomes, Fetal outcomes, Saint Joseph Hospital, University Clinics, Kinshasa

Abstract

Background: Pregnancy in advanced maternal age is any pregnancy occurring after the age of 35. Both late-term and early pregnancies carry a high risk of maternal and fetal morbidity and mortality and are a public health concern. The objective of this study is to identify obstetric outcomes associated with pregnancies in advanced maternal age at Saint-Joseph Hospital and the University Clinics of Kinshasa in the Democratic Republic of Congo.

Methods: This is a cross-sectional analytical study of the records of mothers aged 16 to 50 who gave birth in the maternity wards of Saint-Joseph Hospital and the University Clinics of Kinshasa from 01 January 2018, to 31 December 2022, using non-probability convenience sampling for case selection. Descriptive analyses, analysis of variance (ANOVA), Chi-square tests and logistic regression were used in statistical analyses.

Results: Pregnancies in women with advanced maternal age (AMA) are associated with the risk of pre-eclampsia (aOR: 2.5, p=0.02 for women aged 35-39 and aOR: 3.5, p=0.001 for those over 40) and gestational hypertension (aOR: 12.3, p=0.025 for those over 40), and fetal outcomes associated with pregnancies in women with AMA are prematurity (aOR: 2.7, p=0.001 for women aged 35-39 and aOR: 2.4, p=0.002 for women over 40), low birth weight (aOR: 2.5, p=0.0000 for women aged 35-39 and aOR: 2.4, p=0.002 for women over 40), and low birth weight (aOR: 2.5, p=0.0000 for women aged 35-39). women over 40 years of age) and admissions to neonatal intensive care units (aOR: 2.5, p=0.004 for women over 40 years of age).

Conclusions: Obstetric outcomes associated with pregnancy in older mothers are preeclampsia, prematurity, low birth weight, and admissions to neonatal intensive care units. Our results are useful for prevention through screening and other therapeutic measures of these obstetric and neonatal outcomes in women with AMA with a view to improving their care in our hospitals in Kinshasa.

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