Blinding clues: unveiling the ocular manifestations of preeclampsia

Authors

  • Kunthavvai Thanigachalam Department of Obstetrics and Gynecology, Vijaya Hospital, Chennai, Tamil Nadu, India
  • Usha N. Department of Obstetrics and Gynecology, Vijaya Hospital, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20251610

Keywords:

Preeclampsia, Hypertensive disorder , Pregnancy

Abstract

Preeclampsia is a hypertensive disorder of pregnancy that significantly contributes to maternal and fetal morbidity and mortality. Although its hallmark manifestations include hypertension and proteinuria, systemic complications affecting various organs, including the ocular system, are often under-recognized. Ocular manifestations range from mild visual disturbances to severe complications such as cortical blindness and retinal detachment. These complications reflect the systemic endothelial dysfunction and vascular permeability characteristic of preeclampsia. Early recognition of ocular symptoms can serve as a valuable indicator of disease severity and progression, prompting timely intervention. In this case, a 37-year-old gravida 2, para 1, at 30+6 weeks of gestation presented with severe hypertension (200/110 mm Hg), headache, and loss of vision. A diagnosis of posterior reversible encephalopathy syndrome (PRES) was suggested, likely secondary to cerebral edema associated with preeclampsia. The patient underwent emergency lower-segment caesarean section (LSCS) after stabilization with intravenous Labetalol and magnesium sulphate (MgSO4). Postoperatively, her visual symptoms resolved within six hours, and an ophthalmological evaluation revealed a normal fundus examination. This case shows the importance of recognizing preeclampsia-induced ocular changes, as timely intervention can prevent irreversible complications such as optic neuropathy and permanent vision loss. Multidisciplinary management, including obstetric and ophthalmologic care, is critical to achieving favorable maternal and fetal outcomes. Routine monitoring and ophthalmological evaluations in high-risk pregnancies are essential to early detection and effective management. This case highlights the reversible nature of preeclampsia-induced ocular complications and emphasizes the role of expedited delivery in mitigating severe outcomes.

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References

Liu X, Wen Y, Zou H, Wang S. A model to predict the risk of adverse ocular outcomes in pregnant women. Br J Hosp Med. 2024;85(2):217-25. DOI: https://doi.org/10.21203/rs.3.rs-4454924/v1

Laxmi KV, Ambati SK, Moulika K. A clinical study of ocular changes in pregnant women attending tertiary care hospital, Guntur. Int J Acad Med Pharm. 2024;6(1):1868-72.

Arshad M. Incidence of fundus changes in women with pregnancy-induced hypertension in rural populations of Eastern Uttar Pradesh. J Clin Diagn Res. 2024;14(4):244-51.

Sibai BM, Stella CL. Diagnosis and management of atypical preeclampsia-eclampsia. Am J Obstet Gynecol. 2009;200(5):481.e1-7. DOI: https://doi.org/10.1016/j.ajog.2008.07.048

Cunningham FG, Leveno KJ, Bloom SL, Dashe JS, Hoffman BL, Spong CY. Hypertensive Disorders. In: Williams Obstetrics. 25th edition. New York: McGraw Hill. 2018;710-54.

Fugate JE, Rabinstein AA. Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology, and outstanding questions. Lancet Neurol. 2015;14(9):914-25. DOI: https://doi.org/10.1016/S1474-4422(15)00111-8

Reddy SC, Nalliah S, George SR, Who TS. Fundus changes in pregnancy-induced hypertension. Int J Ophthalmol. 2012;5(6):694-7.

Jha KN, Dutta S, Bhattacharya SK. Ocular manifestations in hypertensive disorders of pregnancy. Nepal J Ophthalmol. 2016;8(15):145-50.

McCance KL, Huether SE, Brashers VL, Rote NS. Hypertensive Disorders in Pregnancy. In: Pathophysiology: The Biologic Basis for Disease in Adults and Children. 8th edition. St. Louis: Elsevier. 2018;977-90.

Amaral LM, Wallace K, Owens M, LaMarca B. Pathophysiology and current clinical management of preeclampsia. Curr Hypertens Rep. 2017;19(8):61. DOI: https://doi.org/10.1007/s11906-017-0757-7

Nandi D, Majumdar S, Banerjee P. Association of retinal sensitivity with gestational hypertension and obesity. J Clin Ophthalmol Res. 2025;10(1):45-51. DOI: https://doi.org/10.4103/jcor.jcor_105_24

Martins MM, Medronho RA, Raymundo CE. Microcephaly and Central Nervous System Abnormalities. Preprints. 2024;6(2):89-96.

Akram S, Ghalib S, Iqbal H. Pregnancy's Invisible Impact on Vision: Tracking Acuity and Refractive Alterations. J Nurs Allied Health. 2024;8(3):112-9. DOI: https://doi.org/10.37939/jnah.v2i04.85

Rozhin K, Gholamreza K, Ali K. Risk factors for congenital nasolacrimal duct obstruction in children under two years. Int Eye Res J. 2025;12(4):203-10.

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Published

2025-05-29

How to Cite

Thanigachalam, K., & N., U. (2025). Blinding clues: unveiling the ocular manifestations of preeclampsia. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 14(6), 2030–2034. https://doi.org/10.18203/2320-1770.ijrcog20251610

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Section

Case Reports