Povidone iodine- antiseptic wound irrigation prior to skin closure at caesarean section to prevent surgical site infection: a randomised study
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20252726Keywords:
Caesarean section, Povidone iodine, Surgical site infectionAbstract
Background: Surgical site infection (SSI) is seen frequently in women undergoing caesarean sections for various indications leading to increase in morbidity amongst the patients in the postpartum period. Irrigation of the subcutaneous tissue before the skin closure with topical antibiotics, povidone iodine or saline has been shown to reduce the risk of SSI. This study was aimed to determine the efficacy of povidone iodine for irrigation of subcutaneous tissue in prevention of SSI.
Methods: This study was performed on 200 subjects undergoing caesarean section who were randomised into two groups- one in which intervention in the form of povidone iodine irrigation was performed and the other in which it was not. The incidence of SSI was calculated in both the groups.
Results: The overall incidence of wound infection in this study was 8.5%. In povidone iodine and no povidone iodine group, the incidence was found to be 9% and 8% respectively.
Conclusions: There was no significant difference between wound infection rates between the povidone iodine and the no povidone iodine group (p value =0.799 by chi square test, chi square value =0.06).
Metrics
References
Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR, Hospital Infection Control Practices Advisory Committee. Guideline for prevention of surgical site infection, 1999. Infect Control Hosp Epidemiol. 1999;20(4):247-80. DOI: https://doi.org/10.1086/501620
Wloch C, Wilson J, Lamagni T, Harrington P, Charlett A, Sheridan E. Risk factors for surgical site infection following cesarean section in England: results from a multicentre cohort study. BJOG. 2012;119(11):1324-33. DOI: https://doi.org/10.1111/j.1471-0528.2012.03452.x
Mueller TC, Loos M, Haller B, Mihaljevic AL, Nitsche U, Wilhelm D, et al. Intraoperative wound irrigation to reduce surgical site infections after abdominal surgery: a systematic review and meta-analysis. Langenbecks Arch Surg 2015;400(2):167-81. DOI: https://doi.org/10.1007/s00423-015-1279-x
National Institute for Health and Clinical Excellence (NICE). Surgical site infection- prevention and treatment of surgical site infection. NICE Clinical Guideline 74. RCOG, London; 2008.
Alexander JW, Solomkin JS, Edwards MJ. Updated recommendations for control of surgical site infections. Ann Surg. 2011;253(6):1082-93. DOI: https://doi.org/10.1097/SLA.0b013e31821175f8
Pradhan GB, Agrawal J. Comparative study of post-operative wound infection following emergency lower segment cesarean section with and without the topical use of fusidic acid. Nepal Med Coll J. 2009;1:189-91.
Mathelier AC. A comparison of postoperative morbidity following prophylactic antibiotic administration by combined irrigation and intravenous route or by intravenous route alone during cesarean section. J Perinat Med. 1992;20(3):177-82 DOI: https://doi.org/10.1515/jpme.1992.20.3.177
Güngördük K, Asicioglu O, Celikkol O, Ark C, Tekırdağ AI. Does saline irrigation reduce the wound infection in cesarean delivery? J Obstet Gynaecol. 2010;30(7):662-6. DOI: https://doi.org/10.3109/01443615.2010.494206
Duff P. Maternal and perinatal infection-bacterial. In: Gabbe S, Niebyl J, Simpson J, Landon M, Galan H, eds. Obstetrics Normal and problem pregnancies 6th edn. Philadelphia, PA: Elsevier Inc; 2012:1140-55. DOI: https://doi.org/10.1016/B978-1-4377-1935-2.00051-X
Owen J, Andrews WW. Wound complications after cesarean sections. Clin Obstet Gynecol. 1994;37(4):842-55. DOI: https://doi.org/10.1097/00003081-199412000-00009