A comparative analysis of qSOFA and SOFA scores for outcome prediction among obstetric patients admitted to intensive care unit at a tertiary care centre

Authors

  • Paridhi Agarwal Department of Obstetrics and Gynecology, L.L.R.M. Medical College, Meerut, India https://orcid.org/0009-0000-9691-0743
  • Rachna Chaudhary Department of Obstetrics and Gynecology, L.L.R.M. Medical College, Meerut, India
  • Shakun Singh Department of Obstetrics and Gynecology, L.L.R.M. Medical College, Meerut, India
  • Pratibha Agarwal Department of Obstetrics and Gynecology, L.L.R.M. Medical College, Meerut, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20252925

Keywords:

Obstetric sepsis, SOFA score, qSOFA, Maternal outcomes, ICU prognosis

Abstract

Background: Sepsis in obstetric patients remains a leading cause of maternal morbidity and mortality, requiring timely recognition and management. The sequential organ failure assessment (SOFA) score is widely used for organ dysfunction assessment, while the Quick SOFA (qSOFA) provides a rapid bedside tool. Their utility in obstetric sepsis, however, is challenged by pregnancy-related physiological changes.

Methods: This prospective observational study was conducted over 18 months (June 2023-November 2024) at L.L.R.M. Medical College, Meerut. Fifty women pregnant, postnatal (≤6 weeks), or postabortal (≤2 weeks) with sepsis diagnosed by SIRS criteria were included. Patients with ectopic pregnancy, malignancy, trauma, or chronic systemic disease were excluded. Clinical examination, laboratory investigations, and SOFA/qSOFA scoring were performed. Statistical analysis was done using SPSS v22 with Chi-square, Fisher’s exact test, independent t-test, and ROC analysis.

Results: SOFA scores showed significant correlation with maternal outcomes: 70% recovered, 20% developed complications, and 10% died (p=0.015). ICU admission was associated with higher qSOFA scores in 80% of patients (p=0.007). SOFA demonstrated superior sensitivity (85%) and specificity (90%) for mortality prediction compared to qSOFA (70% and 75%, respectively; p=0.013).

Conclusion: qSOFA is a useful triage tool for rapid assessment, while SOFA provides greater prognostic accuracy. A combined approach may improve management of obstetric sepsis.

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References

Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, et al. The SOFA score to describe organ dysfunction/failure. Intensive Care Med. 1996;22(7):707–10. DOI: https://doi.org/10.1007/s001340050156

Raith EP, Udy AA, Bailey M, McGloughlin S, MacIsaac C, Bellomo R, et al. Prognostic accuracy of SOFA, SIRS, and qSOFA in ICU patients. JAMA. 2017;317(3):290–300. DOI: https://doi.org/10.1001/jama.2016.20328

Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, et al. Clinical criteria for sepsis: Sepsis-3. JAMA. 2016;315(8):762–74. DOI: https://doi.org/10.1001/jama.2016.0288

Kang MW, Ko SY, Song SW, Kim WJ, Kang YJ, Kang KW, et al. qSOFA and ICU admission prediction. J Trauma Inj. 2021;34(1):3–12. DOI: https://doi.org/10.20408/jti.2020.0048

Kilinc Toker A, Kose S, Turken M. Comparison of SOFA, SIRS, qSOFA, and qSOFA+L. Eurasian J Med. 2021;53(1):40–7. DOI: https://doi.org/10.5152/eurasianjmed.2021.20081

Freund Y, Lemachatti N, Krastinova E, Van Laer M, Claessens YE, Avondo A, et al. Prognostic accuracy of SOFA and qSOFA in ED sepsis. JAMA. 2017;317(3):301–8. DOI: https://doi.org/10.1001/jama.2016.20329

Shankar-Hari M, Phillips GS, Levy ML, Seymour CW, Liu VX, Deutschman CS, et al. New criteria for septic shock. JAMA. 2016;315(8):775–87. DOI: https://doi.org/10.1001/jama.2016.0289

Grooth HJ, Geenen IL, Girbes AR, Vincent JL, Parienti JJ, Oudemans-van Straaten HM. SOFA and mortality prediction. Crit Care Med. 2017;45(5):457–65.

Bowyer L, Robinson HL, Barrett H, Crozier TM, Giles M, Idel I, et al. SOMANZ sepsis guidelines in pregnancy. Aust J Obstet Gynaecol. 2017;57(5):540–51. DOI: https://doi.org/10.1111/ajo.12646

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, et al. Surviving Sepsis Campaign guidelines 2016. Intensive Care Med. 2017;43(3):304–77. DOI: https://doi.org/10.1007/s00134-017-4683-6

Acosta CD, Kurinczuk JJ, Lucas DN, Tuffnell DJ, Sellers S, Knight M. Severe maternal sepsis in the UK. Int J Obstet Anesth. 2014;23(1):28–36.

Say L, Souza JP, Pattinson RC. Maternal near miss: towards a standard tool. Best Pract Res Clin Obstet Gynaecol. 2009;23(3):287–96. DOI: https://doi.org/10.1016/j.bpobgyn.2009.01.007

Souza JP, Cecatti JG, Haddad SM, Parpinelli MA, Costa ML, Katz L, et al. Maternal near miss and sepsis. Reprod Health. 2010;7:22.

Bauer ME, Lorenz RP, Bauer ST, Rao K, Anderson FW. Maternal deaths due to sepsis in the USA. Am J Obstet Gynecol. 2015;212(5):603–8.

Carle C, Rubenfeld GD, Rowan KM. Evolution of sepsis criteria. Intensive Care Med. 2015;41(9):1709–11.

Shapiro NI, Howell MD, Talmor D, Nathanson LA, Lisbon A, Wolfe RE, et al. Serum lactate and mortality prediction. Ann Emerg Med. 2005;45(5):524–8. DOI: https://doi.org/10.1016/j.annemergmed.2004.12.006

Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. Procalcitonin as sepsis marker. Lancet. 1993;341(8844):515–8. DOI: https://doi.org/10.1016/0140-6736(93)90277-N

Prescott HC, Angus DC. Long-term outcomes after sepsis. Lancet Respir Med. 2018;6(3):228–40.

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Published

2025-09-15

How to Cite

Agarwal, P., Chaudhary, R., Singh, S., & Agarwal, P. (2025). A comparative analysis of qSOFA and SOFA scores for outcome prediction among obstetric patients admitted to intensive care unit at a tertiary care centre. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 14(10), 3322–3326. https://doi.org/10.18203/2320-1770.ijrcog20252925

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Original Research Articles