Enhanced myometrial vascularity in hysteroscopy in the elderly: a case report

Deepika Theresa; Usha Rani; Chitra Andrew; Sudhagar Singh

doi:10.18203/2320-1770.ijrcog20253124

Authors

Deepika Theresa Department of Obstetrics and Gynecology, SRIHER, Chennai, Tamil Nadu, India
Usha Rani Department of Obstetrics and Gynecology, SRIHER, Chennai, Tamil Nadu, India
Chitra Andrew Department of Obstetrics and Gynecology, SRIHER, Chennai, Tamil Nadu, India
Sudhagar Singh Department of Obstetrics and Gynecology, SRIHER, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20253124

Keywords:

Enhanced myometrial vascularity, Hysteroscopy, Postmenopausal bleeding, Viagra

Abstract

Sildenafil citrate (Viagra), a selective cGMP specific PDE5 inhibitor, widely used in erectile dysfunction in males, acts on vascular smooth muscle, especially corpus cavernosum. Authors detail a rare case report here, elderly 80-year-old woman, on sildenafil for coronary artery disease and pulmonary hypertension, with a small long standing FIGO 2-5 uterine fibroid, presenting with acute post-menopausal bleeding after 40 years of menopause, hysteroscopy showing enhanced myometrial vascularity and benign histopathology thereafter.

Metrics

Metrics Loading ...

References

Kurjak A, Kupesic S. Ovarian senescence and its significance on uterine and ovarian perfusion. Fert Ster. 1995;64(3):532-7. DOI: https://doi.org/10.1016/S0015-0282(16)57788-7

Jurkovic D, Ross D, Aslam N, Whitehead M. Diurnal variation in uterine artery blood flow in post-menopausal women on oestrogen hormone replacement therapy. Human Reprod. 1999;14(11):2716-9. DOI: https://doi.org/10.1093/humrep/14.11.2716

Vardhan S, Pengoria M. Effect of sildenafil citrate and estradiol valerate on endometrial characteristics in ovulation-induced cycle in women with dysovulatory infertility. J South Asian Fed Obst Gynaecol. 2018;11(3):164-6. DOI: https://doi.org/10.5005/jp-journals-10006-1687

Firouzabadi RD, Davar R, Hojjat F, Mahdavi M. Effect of sildenafil citrate on endometrial preparation and outcome of frozen-thawed embryo transfer cycles: a randomized clinical trial. Iranian J Reprod Med. 2013;11(2):151.

Jain V, Chodankar RR, Maybin JA, Critchley HO. Uterine bleeding: how understanding endometrial physiology underpins menstrual health. Nature Rev Endocrinol. 2022;18(5):290-308. DOI: https://doi.org/10.1038/s41574-021-00629-4

Cavalcanti AL, Bagnoli VR, Fonseca AM, Pastore RA, Cardoso EB, Paixão JS, et al. Effect of sildenafil on clitoral blood flow and sexual response in postmenopausal women with orgasmic dysfunction. Int J Gynaecol Obstet. 2008;102(2):115-9. DOI: https://doi.org/10.1016/j.ijgo.2008.03.020