Sociodemographic and clinical characteristics associated with perinatal outcome in high and low cerebro-umbilical ratio groups

Authors

  • Mahzabin Husain National Institute of Burn and Plastic Surgery, Dhaka, Bangladesh
  • Rubab Sarmin Department of Obstetrics and Gynecology, Sir Salimullah Medical College, Mitford Hospital, Dhaka, Bangladesh
  • Sheikh Imran Alam Department of Anaesthesia, Analgesia and ICM, Bangladesh Medical University, Dhaka, Bangladesh
  • Maliha Tasnim Department of Obstetrics and Gynecology, Chittagong Medical College and Hospital, Chittagong, Bangladesh
  • Salma Akter Department of Obstetrics and Gynecology, 250 Bedded General Hospital, Sirajganj, Bangladesh
  • Jannatul Ferdous Chowdhury Department of Obstetrics and Gynecology, Sarkari Karmachari Hospital, Dhaka, Bangladesh
  • Effat Aziz Department of Obstetrics and Gynecology, East West Medical College, Dhaka, Bangladesh
  • Tasnia Sultana Department of Obstetrics and Gynecology, Ad-Din Akij Medical College, Khulna, Bangladesh

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20253883

Keywords:

Cerebro-umbilical ratio, Perinatal outcomes, Sociodemographics

Abstract

Background: Perinatal morbidity and mortality are largely driven by preterm birth, intrauterine asphyxia from placental insufficiency, and complications related to operative deliveries and medication use. Therefore, this study aimed to assess the association between sociodemographic and clinical characteristics and perinatal outcomes across high and low cerebro-umbilical ratio groups. The aim of the study was to assess the association between sociodemographic and clinical characteristics and perinatal outcomes across high and low cerebro-umbilical ratio groups.

Methods: This prospective cohort study at the department of obstetrics and gynecology, BIRDEM General Hospital, Dhaka (November 2022-February 2024) included 106 women at 29-38 weeks gestation undergoing third-trimester Doppler. Maternal (gestational age, delivery) and fetal outcomes (birth weight, APGAR, respiratory distress, FGR) were assessed in relation to C/U ratio (cutoff 1.01). Data were collected via questionnaire, examination, and ultrasound, analyzed in SPSS 26.0 (p<0.05).

Results: C/U<1.01 was associated with lower education (24.0% versus 57.1% higher secondary), lower income (79,800 versus 68,357 BDT), higher BMI (35.1 versus 33.1 kg/m2), earlier delivery (33.9 vs 36.6 weeks), lower birth weight (1.9 versus 2.6 kg; 96% versus 12.5% LBW), more complicated outcomes (84.0% versus 21.4%), APGAR<7 (68.0% versus 19.6%), NICU admission (74.0% versus 21.4%), respiratory distress (60.0% versus 12.5%), and FGR (18.0% versus 0%). Maternal age, parity, and occupation were similar between groups.

Conclusions: A low cerebro-umbilical ratio is strongly associated with adverse perinatal outcomes, including lower birth weight, earlier delivery, and increased neonatal complications.

 

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References

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Published

2025-11-27

How to Cite

Husain, M., Sarmin, R., Imran Alam, S., Tasnim, M., Akter, S., Ferdous Chowdhury, J., Aziz, E., & Sultana, T. (2025). Sociodemographic and clinical characteristics associated with perinatal outcome in high and low cerebro-umbilical ratio groups. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 14(12), 4193–4198. https://doi.org/10.18203/2320-1770.ijrcog20253883

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Original Research Articles