Navigating dual vulnerability: a rare case of esthesioneuroblastoma in pregnancy

Mamta Kumari Chaudhary; Snigdha Kumari; Vanita Jain; Amanjit Bal; Apinderpreet Singh

doi:10.18203/2320-1770.ijrcog20253565

Authors

Mamta Kumari Chaudhary Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India
Snigdha Kumari Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India
Vanita Jain Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India
Amanjit Bal Department of Histopathology, PGIMER, Chandigarh, India
Apinderpreet Singh Department of Neurosurgery, PGIMER, Chandigarh, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20253565

Keywords:

Esthesioneuroblastoma in pregnancy, Carcinoma breast, Sinonasal tract tumor, Pregnancy

Abstract

Esthesioneuroblastoma (ENB) is a rare malignancy of the sinonasal tract from the olfactory neuroepithelium. Our purpose is to highlight this scarcely described but aggressive tumor presenting in a unique setting where the patient is facing dual vulnerabilities: pregnancy and EBN. We report a case of a 29-year-old female (G2P1L1), 24 weeks pregnant, with a history of progressively increasing left side nasal mass with proptosis, diplopia, nasal discharge, and bleeding from the mass. MRI showed a polypoidal mass in the left nasal cavity with intraorbital and intracranial extensions. The biopsy revealed Hyams grade 2 ENB. Management included craniofacial resection of the lesion and chemoradiation. Caesarean section was performed at 32 weeks, and the patient delivered a baby with a birth weight of 1.463 kg. Early diagnosis and timely intervention, combined with a multidisciplinary approach, for craniofacial resection and chemoradiation, can yield favourable outcomes in this challenging condition.

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