Diverse feto-maternal presentations of chorioangioma: a case series
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20253548Keywords:
Chorioangioma, Intrauterine blood transfusion, Fetal growth restrictionAbstract
Placental chorioangioma is the most common benign non-trophoblastic tumor of the placenta, originating from primitive chorionic mesenchyme and typically being vascular. It has an incidence of 0.6-1% among all pregnancies. The size of the lesion remains the most important factor in prognosis, with small tumors often going unnoticed through the pregnancy without any fetal or maternal complications. Larger lesions (more than 4-5 cm) usually present early in pregnancy and can lead to significant maternal and fetal issues. Late presentation allows more time for fetal maturity and is associated with a lower perinatal mortality rate. Ultrasonography and color Doppler imaging are the main diagnostic tools for placental chorioangioma, showing hypo- and hyper-echoic lesions with vasculature connected to the fetal vascular system. Fetal complications, if they occur, may require intrauterine interventions. We present a series of four cases presenting at different gestational ages with diverse fetal and maternal clinical features and outcomes.
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Guschmann M, Henrich W, Dudenhausen JW. Chorioangiomas-new insights into a well-known problem. II. An immuno-histochemical investigation of 136 cases. J Perinat Med. 2003;31:170-5. DOI: https://doi.org/10.1515/JPM.2003.023
Taori K, Patil P, Attarde V, Singh A, Rangankar V. Chorioangioma of placenta: sonographic features. J Clin Ultrasound. 2008;36:113-5. DOI: https://doi.org/10.1002/jcu.20366
Jauniaux E, Ogle R. Color Doppler imaging in the diagnosis and management of chorioangiomas. Ultrasound Obstet Gynecol. 2000;15:463-7. DOI: https://doi.org/10.1046/j.1469-0705.2000.00127.x
Bashiri A, Furman B, Erez O, Wiznitzer A, Holcberg G, Mazor M. Twelve cases of placental chorioangioma: pregnancy outcome and clinical significance. Arch Gynecol Obstet. 2002;266:53-5. DOI: https://doi.org/10.1007/PL00007501
Haak MC, Oosterhof H, Mouw RJ, Oepkes D, Vandenbussche FP. Pathophysiology and treatment of fetal anemia due to placental chorioangioma. Ultrasound Obstet Gynecol. 1999;14:68-70. DOI: https://doi.org/10.1046/j.1469-0705.1999.14010068.x
Buca D, Lacovella C, Khalil A, Rizzo G, Sirotkina M, Makatsariya A, et al. Perinatal outcome of pregnancies complicated by placental chorioangioma: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2020;55:441-9. DOI: https://doi.org/10.1002/uog.20304
Ma H, Liu Z, Ruan J. Placental chorioangioma and pregnancy outcome: a ten-year retrospective study in a tertiary referral centre. BMC Pregnancy Childbirth. 2023;23:381. DOI: https://doi.org/10.1186/s12884-023-05719-x
Salomon LJ, Alfirevic Z, Berghella V, Bilardo C, Hernandez-Andrade E, Johnsen SL, et al. ISUOG Clinical Standards Committee. Practice guidelines for performance of the routine mid-trimester fetal ultrasound scan. Ultrasound Obstet Gynecol. 2011;37:116-26. DOI: https://doi.org/10.1002/uog.8831
Iacovella C, Chandrasekaran N, Khalil A, Bhide A, Papageorghiou A, Thilaganathan B. Fetal and placental vascular tumors: persistent fetal hyperdynamic status predisposes to poorer long-term neurodevelopmental outcome. Ultrasound Obstet Gynecol. 2014;43:658-61. DOI: https://doi.org/10.1002/uog.13272
Escribano D, Galindo A, Arbues J, Puente JM, Fuente PD. Prenatal management of placental chorioangioma: value of the middle cerebral artery peak systolic velocity. Fetal Diagn Ther. 2006;21:489-93. DOI: https://doi.org/10.1159/000095659
As AK, Hagen P, Webb JB, Wijesinghe D. Therapeutic amnio-drainage in chorioangioma. J Obstet Gynecol. 1997;17:169-70. DOI: https://doi.org/10.1080/01443619750113799
Gajewska K, Herinckx A, Holoye A, D’Haene N, Massez A, Cassart M, et al. Antenatal embolization of a large chorioangioma by percutaneous Glubran 2 injection. Ultrasound Obstet Gynecol. 2010,36:773-5. DOI: https://doi.org/10.1002/uog.8806
Zanardini C, Papageorghiou A, Bhide A, Thilaganathan B. Giant placental chorioangioma: natural history and pregnancy outcome. Ultrasound Obstet Gynecol. 2010;35:332-6. DOI: https://doi.org/10.1002/uog.7451
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