Clinicopathological profile of ovarian tumors in the age group 10-20 years
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20170548Keywords:
Imprint cytology, Laparotomy, Ovarian tumorAbstract
Background: Adolescence is the period of transition from childhood to adulthood. 1% neoplasm occurs in this age group below 17 years, of this, 3% are ovarian neoplasms. Aim was to study retrospectively the clinicopathological profile and outcome of ovarian tumors in the age group 10-20 years in Government Medical College, Kottayam, Kerala, India from January 2008 for six years.
Methods: Fifty Patients who have undergone laparotomy in this institution during the period were taken for study. Data regarding age, mode of presentation, diagnostic methods, treatment and histopathology were recorded. Follow-up was also taken into consideration. Patients with polycystic ovary, corpus luteal cyst, follicular cyst and endometriotic cyst are excluded.
Results: Majority of the patients fall between the age group 15-20 years. Major clinical presentation was pain (40%), followed by abdominal mass. Laparotomy was done for all cases except three where laparoscopy was done. Imprint cytology taken for 3 cases. Histopathology showed malignant tumors in 6 cases and benign tumors in 44 cases. Epithelial tumors outnumbered germ cell tumors.
Conclusions: This study shows the predominance of epithelial neoplasms in the age group 10-20 years. Proportion of malignancy is 12%.
References
Consolidated report of hospital based cancer registries: 2012-2014. Avialable from: http:// ncrpindia.org/ALL_NCRP_REPORTS/HBCR_REPORT_2012_2014/index.htm.
Devi KU. Current status of gynecological cancer care in India. J Gynecol Oncol. 2009;20(2):77-80.
Grovas A, Fremgen A, Rauck A, Ruyman D, Hut- chinson C, Winchester D, et al. The national cancer data base report on patterns of childhood cancers in the United States. Cancer. 1997;80:2321.
Deligeoroglou E, Eleftheriades M, Shiadoes V. Ovarian masses during adolescence: clinical, ultrasonographic and pathological findings, serum tumour markers, and endocrinological profile. Gynaecol Endocrinol. 2004;19:1-8.
Rathore R, Sharma S, Arora D. Spectrum of childhood and adolescent ovarian tumours in India: 25 Years’ experience at a single institution. Maced J Med Sci. 2016;4(4):551-5.
Chellamma VK. Adolescent Ovarian 2011 KFOG Vol.5 No:3 P 3-5 5,7
Bhattacharya NK, De A. Ovarian tumours in pediatric age group- A clinic-patho study of 10 years cases in West Bengal India. Indian J Med Paediatr Oncol. 2010;31(2):54-57.
Amatya A, Rana A, Gurung G. Ovarian tumours in childhood and adolescents- our eight years experiences. NJOG. 2008;3(1):39-42.
Choudry A, Bangash N, Malik A, Choudry H. A clinico pathological review of 15 cases 2008. J Ayub Med coll Abbottabad. 2008;20(4):18-21.
Hernon M, McKenna J, Busby G, Sanders C, Garden A. The histology management of ovarian cysts found in children and adolescent presenting to a children hospital from 1991 to 2007. BJOG. 2010;117(2):181-4.
Chitrathara K, Rajaram S, Maheswari A. Ovarian Cancer: comprehensive and contemporary management. 1st ed. Jaypee Brothers Medical Publishers (P) Ltd.; 2009:121-122.
Piek JM, Verheijen RH, Kenemans P, Massuger LF, Bulten H, van Diest PJ. BRCA ½-related ovarian cancers are of tubal origin A hypothesis. Gynecol Oncol. 2003;90;491
Gracia CR, Chang J, Kondapalli L, Prewitt M, Carlson CA, Mattei P, et al. Ovarian tissue cryopreservation for fertility preservation in cancer patients: Successful establishment and feasibility of a multidisciplinary collaboration. J Assist Reprod Genetics. 2012;29(6):495-502.