DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20171450

Placental mesenchymal dysplasia

Kanwal Gujral, Nandita Dimri, Sunita Bhalla, Chandra Mansukhani, Sakshi Nayar

Abstract


Placental Mesenchymal Dysplasia (PMD) is a rarely encountered placental lesion often associated with high fetal mortality and morbidity. We report here a case of PMD with a favourable outcome. The salient features of diagnosis, management and literature review are discussed.


Keywords


Cystic Placenta, Placental Mesenchymal Dysplasia

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References


Moscoso G, Jauniaux E, Hustin J. Placental vascular anomaly with diffuse mesenchymal stem villous hyperplasia. A new clinico-pathological entity? Pathol Res Pract. 1991;187:324-8.

Arizawa M, Nakayama M. Suspected involvement of the X chromosome inplacental mesenchymal dysplasia. Congenit Anom. 2002;42:309-17.

Cohen MC, Roper EC, Sebire NJ, Stanek J, Anumba DOC. Placental mesenchymal dysplasia associated with fetal aneuploidy. Prenat Diagn. 2005;25:187-92.

Ernst LM. Placental mesenchymal dysplasia. J Fetal Med. 2015;2(3):127-33.

Chen CP, Chern SR, Wang TY, Haung MC, Chaung CY. Pregnancy with concomitant chorangioma and placental vascular malformation with mesenchymal hyperplasia. Hum Reprod. 1997;12:2553-6.

Kaiser Rogers KA, McFadden DE, Livasy CA, Dansereau J, Jiang R, Knops JF et al. Androgenetic/biparental mosaicism causes placental mesenchymal dysplasia. J Med Genet. 2006;43:187-92.

Maher ER, Reik W. Bechwith-Wiedemann syndrome: imprinting in clusters revisited. J Clin Invest. 2000;105:247-52.

Zahida P, Fraser R, Jeffery LK, Karen ST. Placental mesenchymal dysplasia. Arch Pathol Lab Med. 2007;131:131-7.

Kuwabara Y, Shima Y, Araki T, Shin S. Mesenchymal stem villous hyperplasia of the placenta and fetal growth restriction. Obstet Gynecol. 2001;98:940-3.

Pham T, Steele J, Stayboldt C, Chan L, Benirschke K. Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: a report of 11 new cases and a review of the literature. Am J Clin Pathol. 2006;126:67-78.

Cohen MM Jr. Beckwith Wiedemann syndrome: historical, clinicopathological, and etiopathogenetic perspectives. Pediatr Dev Pathol. 2005;8:287-304.

McCowan L, Becroft D. Beckwith Wiedemann syndrome, placental abnormalities, and gestational proteinuric hypertension. Obstet Gynecol. 1994;83:813-7.

Nayeri UA, West AB, Grossetta Nardini HK, Copels JA. Systematic review of sonographic findings of placental mesenchymal dysplasia and subsequent pregnancy outcome. Ultrasound Obstet Gynecol. 2013;41:366-74.