Mature placental teratoma, fetiform type: a rare case report
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20260345Keywords:
Placental teratoma, Acardius amorphus, Germ cell tumorAbstract
A placental teratoma is a rare benign tumor of germ cell origin. Fewer than 50 cases have been reported worldwide. The fetiform variant poses a diagnostic challenge in distinguishing it from acardius amorphus, as it resembles fetal structures without true axial organization. Here we present a case of mature placental teratoma, fetiform type, in a 34-year-old G2P1L1 woman who delivered a healthy male infant at term via uncomplicated vaginal delivery. Post-delivery, a 7.0×6.5×3.5 cm hairy mass was identified on the fetal surface of placenta, supplied by placental vessels without Wharton's jelly or an umbilical cord. The tumor was not reported on antenatal scans. On Gross examination, a heterogeneous solid mass with yellowish areas and few bony components was identified; histopathology confirmed mature tissues from all three germ layers, including ectoderm, mesoderm, endoderm, without immature, malignant, or any organized fetal structures. Due to absent axial skeleton, polarity, and segmentation diagnosis favours teratoma over acardius amorphus. Etiology suggests aberrant migration of germ cells between amnion and chorion. There were no adverse neonatal or maternal outcomes in our case. This case report adds to the limited literature of placental teratoma.
Metrics
References
Morville P. Une teratoma placentaire. Gynecol Obstet (Paris). 1925;2:29-32.
Fox H, Butler‐Manuel R. A teratoma of the placenta. J Pathol Bacteriol. 1964;88(1):137-40. DOI: https://doi.org/10.1002/path.1700880118
Shimojo H, Itoh N, Shigematsu H, Yamazaki T. Mature teratoma of the placenta. Pathol Int. 1996;46(5):372-5. DOI: https://doi.org/10.1111/j.1440-1827.1996.tb03623.x
Gruca-Stryjak KA, Ropacka-Lesiak MA, Bręborowicz GH. Nontrophoblastic placental tumors. Arch Perinatal Med. 2011;17(2):113-7.
Le Vance J, Gurney L, Hodgetts Morton V, Morris RK, Marton T. Non‐trophoblastic tumours of the placenta: pathophysiology, diagnosis and management. Obstet Gynaecol. 2025;27(2):91-103. DOI: https://doi.org/10.1111/tog.12970
Jha P, Paroder V, Mar W, Horowtiz JM, Poder L. Multimodality imaging of placental masses: a pictorial review. Abdominal Radiol. 2016;41(12):2435-44. DOI: https://doi.org/10.1007/s00261-016-0919-0
Gaffar BA, Hotait HY, Gamlouch SF, Swalaha NJ. Placental teratoma or fetus acardius amorphous? Hematol Oncol Stem Cell Therapy. 2008;1(1):57-61. DOI: https://doi.org/10.1016/S1658-3876(08)50062-8
Kudva R, Monappa V, Rai L. Placental teratoma: a diagnostic dilemma with fetus acardius amorphous. Indian J Pathol Microbiol. 2010;53(2):378-9. DOI: https://doi.org/10.4103/0377-4929.64293
Esin S, Ozyuncu O, Turgal M, Karabulut E, Celen S, Tarim E. Placenta Teratoma or Acardiac Fetus Amorphous: DNA Genotyping Shows It's Good to be Different. Fetal Pediatr Pathol. 2022;41(1):147-53. DOI: https://doi.org/10.1097/PGP.0000000000000769
Fox H. Pathology of the placenta. Major Probl Pathol. 1978;7:343-8.
Block D, Cruikshank S, Kelly K, Stanley M. Placental teratoma. Int J Gynecol Obstet. 1991;34(4):377-80. DOI: https://doi.org/10.1016/0020-7292(91)90608-8
Smith LA, Pounder DJ. A teratoma-like lesion of the placenta: a case report. Pathology. 1982;14(1):85-7. DOI: https://doi.org/10.3109/00313028209069047
Ahmed N, Kale V, Thakkar H, Hanchate V, Dhargalkar P. Sonographic diagnosis of placental teratoma. J Clin Ultrasound. 2004;32(2):98-101. DOI: https://doi.org/10.1002/jcu.10231
Meinhard K, Dimitrov S, Nicolov A, Dimitrova V, Vassilev N. Placental teratoma-a case report. Pathol Res Pract. 1999;195(9):649-51. DOI: https://doi.org/10.1016/S0344-0338(99)80130-7
Chandy RG, Korula A, Seshadri L. Teratoma of the placenta. Aust N Zeal J Obstet Gynaecol. 2002;42(5):556-7. DOI: https://doi.org/10.1111/j.0004-8666.2002.548_6.x
Elagöz S, Aker H, Cetin A. Placental teratoma: a case report. Europ J Obstetr Gynecol Reproduct Biol. 1998;80(2):263-5. DOI: https://doi.org/10.1016/S0301-2115(98)00090-6
Prashanth A, Lavanya R, Girisha KM, Mundkur A. Placental teratoma presenting as a lobulated mass behind the neck of fetus: a case report. Case Rep Obstet Gynecol. 2012;2012(1):857230. DOI: https://doi.org/10.1155/2012/857230
Khormoji NN, Soleimani V, Sheikhhasani S. Mature placental teratoma: a case report. Biomed Res Therapy. 2022;9(1):4818-21. DOI: https://doi.org/10.15419/bmrat.v9i1.718
Unger JL. Placental teratoma. Am J Clin Pathol. 1989;92(3):371-3. DOI: https://doi.org/10.1093/ajcp/92.3.371
García-Riaño DA, Aragón-Mendoza RL, Méndez-Sarmiento CP. Teratoma placentario: reporte de un caso y revisión de la literatura. Revista Colombiana de Obstetricia y Ginecología. 2014;65(3):262-7. DOI: https://doi.org/10.18597/rcog.54
Lian-tang W, Xing-hua D, Mao-chang L. Placental teratoma: A case report and review of the literature. Pathol Res Pract. 1995;191(12):1267-70. DOI: https://doi.org/10.1016/S0344-0338(11)81138-6
Buyukkurt S, Evrüke C, Zeren H, Demir C, Ozgunen FT, Misirlioglu S. Prenatal diagnosis of placental teratoma: A case report. Europ J Obstet Gynecol Reproduct Biol. 2009;146(2):233-4. DOI: https://doi.org/10.1016/j.ejogrb.2009.06.009
Downloads
Published
How to Cite
Issue
Section
