Giant uterine leiomyoma mimicking leiomyosarcoma: a diagnostic dilemma — a case report
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20262567Keywords:
Leiomyoma, Leiomyosarcoma, Pelvic mass, Histopathology, Uterine tumorAbstract
Uterine leiomyomas are common benign tumors; however, giant leiomyomas are rare and can mimic malignant uterine neoplasms. We report a case of a 41-year-old nulligravid woman presenting with a massive abdominopelvic mass of uncertain origin. Imaging findings were inconclusive and raised suspicion of leiomyosarcoma. The patient underwent exploratory laparotomy with total abdominal hysterectomy and bilateral salpingectomy. Histopathological and immunohistochemical examination confirmed a benign leiomyoma. This case highlights the diagnostic challenges posed by large uterine masses and emphasizes the importance of histopathology in establishing a definitive diagnosis.
References
Kalyan S, Sharma S. Giant uterine leiomyoma: a case report with literature review. Int J Reprod Contracept Obstet Gynecol. 2018;7(11):4780-3.
Stewart EA. Uterine fibroids. Lancet. 2001;357(9252):293-8.
Bhatta N. Tumors of the corpus uteri. In: Jeffcoate N, ed. Jeffcoate's Principles of Gynaecology. 6th ed. London: Arnold. 2001;470-88.
Rajesh S, Adam M. Benign metastasizing leiomyoma: a sheep in wolf's clothing. Community Oncol. 2013;10(4):122-5.
Bulun SE. Uterine fibroids. N Engl J Med. 2013;369(14):1344-55.
Giuntoli RL 2nd, Metzinger DS, DiMarco CS, Cha SS, Sloan JA, Keeney GL, et al. Leiomyosarcoma of the uterus: prognostic indicators, surgical management and adjuvant therapy. Gynecol Oncol. 2003;89(3):460-9.
Roberts ME, Aynardi JT, Chu CS. Uterine leiomyosarcoma: a review of the literature and update on management options. Gynecol Oncol. 2018;151(3):562-72.
Bell SW, Kempson RL, Hendrickson MR. Problematic uterine smooth muscle neoplasms: a clinicopathologic study of 213 cases. Am J Surg Pathol. 1994;18(6):535-58.