Cancer cervix (adenocarcinoma) with cardiac metastasis: a rare case report and review of literature
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20262148Keywords:
Cancer cervix, Adenocarcinoma, HPV infection, Cardiac metastasis, Malignant pericardial effusionAbstract
Carcinoma of the cervix is one of the leading malignancies in females worldwide, more prominent in developing countries. Squamous cell carcinoma is the most common histology with around 70% cases and Adenocarcinoma follows with 10-30%. Cardiac metastasis is very rare and difficult to diagnose with a reported incidence of 0.3% to 1.23% and is generally based on autopsy findings, only few cases of antemortem diagnosis of malignant pericardial effusion secondary to cervical carcinoma have been reported so far. The prognosis is poor and the longest reported survival so far is of 13 months. We hereby present a rare case report of adenocarcinoma of the cervix metastasizing to the heart and presenting with malignant pericardial effusion. The patient succumbed within one month of diagnosis.
References
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209-49.
Hu K, Wang W, Liu X, Meng Q, Zhang F. Comparison of treatment outcomes between squamous cell carcinoma and adenocarcinoma of cervix after definitive radiotherapy or concurrent chemoradiotherapy. Radiat Oncol. 2018;13(1):249.
Hodgson A. Cervical Adenocarcinomas: A Heterogeneous Group of Tumors with Variable Etiologies and Clinical Outcomes. Arch Pathol Lab Med. 2019;143(1):34-46.
Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. 2019;393(10167):169-82.
Nandakumar A, Anantha N, Venugopal TC. Incidence, mortality and survival in cancer of the cervix in Bangalore, India. Br J Cancer. 1995;71(6):1348-52.
Grigsby PW. The prognostic value of PET and PET/CT in cervical cancer. Cancer Imaging. 2008;8:146-55.
Byun SW, Park ST, Ki EY, Song H, Hong SH, Park JS. Intracardiac metastasis from known cervical cancer: a case report and literature review. World J Surg Oncol. 2013;11:107.
Ghosh I, Mandal R, Kundu P, Biswas J. Association of genital infections other than human papillomavirus with pre-invasive and invasive cervical neoplasia. J Clin Diagn Res. 2016;10(2):XE01-6.
Bhandari V, Kausar M, Naik A, Batra M. Unusual metastasis from carcinoma cervix. J Obstet Gynaecol India. 2016;66(5):358-62.
Yu X, Wang Z, Zhang Z, Liu Y, Huang J. Postoperation of cervical cancer with intestine metastasis: A case report and literature review. World J Surg Oncol. 2016;14(1):2.
Zhou S, Peng F. Patterns of metastases in cervical cancer: A population-based study. Int J Clin Exp Pathol. 2020;13(7):1615-23.
Sasidharan A, Hande V, Mahantshetty U, Shrivastava SK. Cardiac metastasis in cervical cancer. BJR Case Rep. 2016;2(2):20150300.
Nguyen O, Ouellette D. Survival post surgery for malignant pericardial effusion. Clin Pract. 2011;1(2):e38.
Rodríguez-Rosales YE, Salazar-Mejía CE, Soto-Martínez BA, Hernández-Barajas D, Vidal-Gutiérrez O, Gómez-Macías GS. Cardiac Tamponade as an Initial Manifestation of Cervical Cancer. Case Rep Oncol Med. 2019;2019:7524797.
Burazor I, Aviel-Ronen S, Imazio M, Goitein O, Perelman M, Shelestovich N, et al. Metastatic cardiac tumors: from clinical presentation through diagnosis to treatment. BMC Cancer. 2018;18(1):202.
Downloads
Published
How to Cite
Issue
Section
