Correlation of prolactin and thyroid disorders in infertile women


  • Priyanka Sharma Department of Obstetrics and Gynecology, IGMC, Shimla, Himachal Pradesh, India
  • Anita Pal Department of Obstetrics and Gynecology, IGMC, Shimla, Himachal Pradesh, India
  • Rajeev Sood Department of Obstetrics and Gynecology, IGMC, Shimla, Himachal Pradesh, India
  • Saroj Jaswal Department of Biochemistry, IGMC, Shimla, Himachal Pradesh, India
  • Suman Thakur Department of Obstetrics and Gynecology, IGMC, Shimla, Himachal Pradesh, India
  • Anupam Sharma Department of Obstetrics and Gynecology, IGMC, Shimla, Himachal Pradesh, India



Galactorrhoea, Hypothyroidism, Hyperprolactinaemia, Infertility, Oligomenorrhoea


Background: The objective of the study was to review the impact of thyroid status on the fertility and to study the prevalence of hyperprolactinaemia in infertility.

Methods: A total of 150 subjects were divided into 3 groups: 50 primary infertility, 50 secondary infertility and 50 controls. The incidence of hyperprolactinaemia and thyroid disorders was studied in all the three groups.

Results: The incidence of hyperprolactinaemia was 41% in all infertile subjects (60% with primary and 22% in secondary infertility) and 6% in controls. The incidence of hypothyroidism was 17% in infertility (18% in primary and 16% in secondary infertility) and 8% in controls.

Conclusions: In this study there is a positive correlation between increased prolactin levels and hypothyroidism and such patients’ exhibit ovulatory failure. All patients with infertility should undergo prolactin levels and thyroid profile.


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