Maternal outcomes in postpartum haemorrhage: a prospective observational study of 100 women at a tertiary referral centre in Kutch, Gujarat

Authors

  • Nirali P. Vaghasia Department of Obstetrics and Gynaecology, Gujarat Adani Institute of Medical Sciences and G.K. General Hospital, Bhuj, Kutch, Gujarat, India https://orcid.org/0009-0008-9559-6084
  • Mamtaben T. Ganasva Department of Obstetrics and Gynaecology, Gujarat Adani Institute of Medical Sciences and G.K. General Hospital, Bhuj, Kutch, Gujarat, India
  • Divya Tekani Department of Obstetrics and Gynaecology, Gujarat Adani Institute of Medical Sciences and G.K. General Hospital, Bhuj, Kutch, Gujarat, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20264004

Keywords:

Postpartum haemorrhage, Maternal mortality, Severe maternal outcome, Obstetric hysterectomy, Blood transfusion, Referral and consultation

Abstract

Background: Postpartum haemorrhage is the leading direct cause of maternal death worldwide and the commonest cause of maternal death in India. Outcomes at district-level referral centres serving rural populations are less well described than those at urban teaching hospitals. This study evaluated maternal outcomes in such a setting.

Methods: This prospective observational study included 100 women with postpartum haemorrhage at a tertiary referral centre in Bhuj, Gujarat, between April 2024 and October 2025. Demographic profile, aetiology, management and outcome were recorded. A composite severe maternal outcome was defined a priori as obstetric hysterectomy, transfusion of four or more units, or maternal death. Associations were tested using Fisher's exact test.

Results: Seventy-four women were unbooked, 68 rural and 54 referred after delivering elsewhere. Mean age was 29.2 years (SD 5.6) and mean parity 3.56 (SD 2.13). Uterine atony was the leading cause (68%), followed by genital tract trauma (19%). Surgical intervention was required in 66%, most commonly uterine packing (30%); hysterectomy in 12%. Blood products were transfused in 80%. Postpartum anaemia was the commonest morbidity (34%). Eight women died (8%). Severe maternal outcome occurred in 17% and was associated with caesarean delivery (27.9% versus 8.8%, p=0.016) and previous caesarean section (35.0% versus 12.5%, p=0.040), but not with anaemia or preeclampsia.

Conclusions: Case fatality was substantially higher than in comparable published series. Severe maternal outcome clustered around operative delivery and uterine scar rather than antenatal risk factors, suggesting that reducing the interval to definitive haemorrhage control matters more than antenatal risk stratification in this setting.

References

Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J, et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health. 2014;2(6):e323-33.

Coomarasamy A, Sindhu KN, Gallos I, Periyathambi N, Price MJ, Yunas I, et al. Postpartum haemorrhage: epidemiology, consequences, and missed opportunities. Lancet. 2026;408(10549):62-73.

Cresswell JA, Alexander M, Chong MYC, Link HM, Pejchinovska M, Gazeley U, et al. Global and regional causes of maternal deaths 2009-20: a WHO systematic analysis. Lancet Glob Health. 2025;13(4):e626-34.

Bahadur A, Singhvi S, Heda A. Trends of maternal mortality in India. Indian Obstet Gynaecol. 2025;15(2):28-33.

Carroli G, Cuesta C, Abalos E, Gulmezoglu AM. Epidemiology of postpartum haemorrhage: a systematic review. Best Pract Res Clin Obstet Gynaecol. 2008;22(6):999-1012.

Calvert C, Thomas SL, Ronsmans C, Wagner KS, Adler AJ, Filippi V. Identifying regional variation in the prevalence of postpartum haemorrhage: a systematic review and meta-analysis. PLoS One. 2012;7(7):e41114.

Demissie DB, Kaura DK, Gebhardt S. Global burden, disparities, and determinants of postpartum haemorrhage among women who gave birth: an umbrella review of systematic reviews and meta-analyses. Front Reprod Health. 2025;7:1721550.

Bienstock JL, Eke AC, Hueppchen NA. Postpartum hemorrhage. N Engl J Med. 2021;384(17):1635-45.

Escobar MF, Nassar AH, Theron G, Barnea ER, Nicholson W, Ramasauskaite D, et al. FIGO Safe Motherhood and Newborn Health Committee. FIGO recommendations on the management of postpartum hemorrhage 2022. Int J Gynaecol Obstet. 2022;157(Suppl 1):3-50.

Sheldon WR, Blum J, Vogel JP, Souza JP, Gülmezoglu AM, Winikoff B. WHO Multicountry Survey on Maternal and Newborn Health Research Network. Postpartum haemorrhage management, risks, and maternal outcomes: findings from the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG. 2014;121(1):5-13.

Royal College of Obstetricians and Gynaecologists. Prevention and management of postpartum haemorrhage. Green-top Guideline No. 52. BJOG. 2017;124(5):e106-49.

World Health Organization. Evaluating the quality of care for severe pregnancy complications: the WHO near-miss approach for maternal health. 2011. Available at: https://www.who.int/publications/i/ item/9789241502221. Accessed on 26 August 2026.

Souza JP, Cecatti JG, Haddad SM, Parpinelli MA, Costa ML, Katz L, et al. The WHO maternal near-miss approach and the maternal severity index model (MSI): tools for assessing the management of severe maternal morbidity. PLoS One. 2012;7(8):e44129.

Singh J, Metgud CS. Study of “three delay model” of maternal morbidity and mortality in two tertiary care hospitals of Belagavi. Indian J Health Sci Biomed Res KLEU. 2021;14(2):234-8.

Jogi SR, Ekka AR. Maternal mortality review by three delay model: a retrospective study from a tertiary care hospital of Chhattisgarh. Int J Reprod Contracept Obstet Gynecol. 2021;10(1):262-7.

Tondge G, Burande A. A retrospective study of cases of postpartum hemorrhage at tertiary health care center. Indian J Obstet Gynecol Res. 2018;5(3):322-6.

Ramani S, Vijaya B. Prevalence and outcome of primary postpartum haemorrhage in a tertiary care hospital: a hospital record based study. New Indian J OBGYN. 2023;9(2):308-13.

Suarez S, Conde-Agudelo A, Borovac-Pinheiro A, Suarez-Rebling D, Eckardt M, Theron G, et al. Uterine balloon tamponade for the treatment of postpartum hemorrhage: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;222(4):293.e1-e52.

Shetty S, Moray K, Sachin O, Chaurasia H, Joshi B. A narrative review comparing clinical effectiveness of commonly used uterine balloon tamponade devices for postpartum haemorrhage management in India. Int J Reprod Contracept Obstet Gynecol. 2022;11(10):2924-42.

Chaudhary V, Singh M, Nain S, Reena F, Aggarwal K, Biswas R, et al. Incidence, management and outcomes in women undergoing peripartum hysterectomy in a tertiary care centre in India. Cureus. 2021;13(3):e14171.

Sherkhane V, Palve T. A study of management and outcomes of postpartum haemorrhage in singleton pregnancy at a tertiary care hospital: an observational study. Int J Reprod Contracept Obstet Gynecol. 2026;15(8):3050-4.

Moitra B, Oraon BP. Study of cases of post-partum hemorrhage after spontaneous vaginal delivery in labour room of a tertiary care center, Ranchi, Jharkhand, India. Int J Reprod Contracept Obstet Gynecol. 2020;9(4):1540-4.

Omotayo MO, Abioye AI, Kuyebi M, Eke AC. Prenatal anemia and postpartum hemorrhage risk: a systematic review and meta-analysis. J Obstet Gynaecol Res. 2021;47(8):2565-76.

Mansukhani R, Shakur-Still H, Chaudhri R, Bello S, Muganyizi P, Kayani A, et al; WOMAN-2 trial collaborators. Maternal anaemia and the risk of postpartum haemorrhage: a cohort analysis of data from the WOMAN-2 trial. Lancet Glob Health. 2023;11(8):e1249-59.

Dasa TT, Okunlola MA, Dessie Y. Effect of grand multiparity on adverse maternal outcomes: a prospective cohort study. Front Public Health. 2022;10:959633.

Humphrey MD. Is grand multiparity an independent predictor of pregnancy risk? A retrospective observational study. Med J Aust. 2003;179(6):294-6.

DeBolt CA, Rao MG, Limaye MA, London V, Sagaram D, Roman AS, et al. Grand multiparity and obstetric outcomes in a contemporary cohort: the role of increasing parity. Am J Perinatol. 2024;41(7):815-25.

Nelissen E, Mduma E, Broerse J, Ersdal H, Evjen-Olsen B, van Roosmalen J, et al. Applicability of the WHO maternal near miss criteria in a low-resource setting. PLoS One. 2013;8(4):e61248.

WOMAN Trial Collaborators. Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. Lancet. 2017;389(10084):2105-16.

Downloads

Published

2026-10-29

How to Cite

Vaghasia, N. P., Ganasva, M. T., & Tekani, D. (2026). Maternal outcomes in postpartum haemorrhage: a prospective observational study of 100 women at a tertiary referral centre in Kutch, Gujarat. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 15(11), 4530–4537. https://doi.org/10.18203/2320-1770.ijrcog20264004

Issue

Section

Original Research Articles