Pregnancy related acute kidney injury: nondialytic management

Kaliki Hymavathi Reddy, K. Praveen Kumar, Keerthi Rajan, Sabreen Shaik


Acute Kidney Injury (AKI) is associated with increased mortality and morbidity unless timely diagnosed & promptly managed. An understanding of the renal physiologic changes that occur during pregnancy is essential for Proper evaluation, diagnosis, and management of Pregnancy Related AKI (PRAKI). In the general population, AKI can occur from prerenal, intrinsic/renal, and post-renal causes. Major causes of pre-renal azotemia include hyperemesis gravidarum and uterine hemorrhage in the setting of placental abruption. Intrinsic etiologies include infections from acute pyelonephritis and septic abortion, bilateral cortical necrosis, and acute tubular necrosis. Particular attention should be paid to specific conditions that lead to AKI during the second and third trimesters, such as preeclampsia, HELLP syndrome, acute fatty liver of pregnancy, and TTP-HUS. An understanding of the various etiologies of AKI in the pregnant patient is key to the appropriate clinical management & prevention of adverse maternal/fetal outcomes. Sometimes PRAKI may require intensive management and even dialysis adding additional economical burden to the patient. We here, with report an interesting case of PRAKI diagnosed & managed in time by simple medical measures thus delivering an effective treatment at a much lesser cost.


Pregnancy, Preeclampsia, Acute kidney injury

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