Malignant mixed germ cell tumor of ovary: a rare case report

Authors

  • Bhawana Tiwary Department of Obstetrics & Gynaecology, AIIMS, Phulwarisharif, Patna, Bihar, India
  • Hemali Heidi Sinha Department of Obstetrics & Gynaecology, AIIMS, Phulwarisharif, Patna, Bihar, India
  • Vivek K. Pandey Department of Pathology, Darbhanga Medical College, Darbhanga, Bihar, India

Keywords:

Malignant mixed germ cell tumor, Dysgerminoma, Yolk sac tumor, Endodermal sinus tumor

Abstract

Ovarian germ cell tumors are very rare and affect mainly young girls and women. One of the most remarkable advances in oncology is in the treatment of malignant ovarian germ cell tumors. The two histological groups are: dysgerminomas and non dysgerminomatous tumors. We report a case of a 29 years old multiparous woman who presented with persistent pain abdomen and was diagnosed to have a malignant mixed germ cell tumor comprising of both dysgerminoma and yolk sac tumor (endodermal sinus tumor). 

References

Lim FK, Chanrachakul B, Chong SM, Ratnam SS. Malignant ovarian germ cell tumours: experience in the national university of hospital of Singapore. Ann Acad Med Singapore. 1998;27(5):657-61.

Gershenson DM, Del Junco G, Copeland LJ, Rutledge FN. Mixed germ cell tumors of the ovary. Obstet Gynecol. 1984;64(2):200-6.

Gershenson DM. Update on malignant ovarian germ cell tumors. Cancer. 1993;71(4 Suppl):1581-90.

Kurman RJ, Norris HJ. Malignant germ cell tumors of the ovary. Hum Pathol. 1977;8(5):551-64.

Berek JS, Adashi EY, Hillard PA. HCG and Alpha-fetoprotein. In: Berek JS, Adashi EY, Hillard PA, eds. Novak’s Gynecology. 12th ed. Baltimore: Williams & Wilkins; 1996.

Kurman RJ, Norris HJ. Embryonal carcinoma of the ovary: a clinicopathologic entity distinct from endodermal sinus tumour resembling embryonal carcinoma of adult testis. Cancer. 1976;38(6):2420-33.

Zanetta G, Bonazzi C, Cantu M, Binidagger S, Locatelli A, Bratina G, et al. Survival and reproductive function after treatment of malignant germ cell ovarian tumors. J Clin Oncol. 2001;19(4):1015-20.

Downloads

Published

2017-02-06

Issue

Section

Case Reports