Leiomyosarcoma of the ovary associated with leiomyoma of uterus: a case report

Chitra Thyagaraju, Jayalakshmi Durairaj, Sujatha Venkataraman


Leiomyosarcoma of the ovary is a rare disease accounting for <1% of all sarcomas. It occurs mainly in post-menopausal women with aggressive behaviour and poor prognosis. Surgery is the cornerstone of treatment, while the role of chemotherapy and radiotherapy is still not clear. This paper presents the case of a post-menopausal woman who is diagnosed with primary leiomyosarcoma of the ovary along with multiple leiomyoma of the uterus, and who receives a surgical approach and currently achieving 25 months free from disease.


Leiomyosarcoma of ovary

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Enzinger FM, Weiss SW. Soft tissue sarcoma. The CV Mosby Co. 1988;2:402.

Kurian RR, Preethi J, Remadevi AV. Leiomyosarcoma of ovary: a case report. Indian J Pathol Microbiol. 2005;48(1):19-20.

Rasmussen CC, Skilling JS, Sorosky JI, Lager DJ, Buller RE. Stage IIIC ovarian leiomyosarcoma in a premenopausal woman with multiple recurrences: prolonged survival with surgical therapy. Gynecol Oncol. 1997;66(3):519-25.

Bouie SM, Cracchiolo B, and Heller D. Epithelioid leiomyosarcoma of the ovary. Gynecol Oncol. 2005;97:697-9.

Taşkin S, Taşkin EA, Uzüm N, Ataoğlu O, Ortaç F. Primary ovarian leiomyosarcoma: a review of the clinical and immunohistochemical features of the rare tumor. Obstet Gynecol Surv. 2007;62:480-6.

Prat J, Fox H. Mesenchymal tumour of the ovary. Obstet Gynaecol. 1987;2(2):701-2.

Dixit S, Singhal S, Baboo HA, Vyas RK, Neema JP, Murthy R, et al. Leiomyosarcoma of the ovary - a case report. J Postgrad Med. 1993;39(3):151-3.

Arslan OS, Sumer C, Cihangiroglu G, Kanat-Pektas M, Gungor T. A rare tumor of the female genital tract: primary ovarian leiomyosarcoma. Arch Gynecol Obstet. 2011;283:83-5.

Kumar RG. Leiomyosarcoma of probably ovarian or broad ligament origin. Br J Obstet Gynecol. 1982;88:327-9.