Prevalence of cervical intraepithelial neoplasia & cervical carcinoma in ever married women in rural area of a district in Haryana
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20150098Keywords:
CIN, Cervical carcinoma, Prevalence, Ever married women, RuralAbstract
Background: Objectives: To find the burden of cervical intraepithelial neoplasia and cervical carcinoma in ever married rural women and to create awareness for its prevention and management.
Methods: The present cross-sectional study was undertaken in Block Beri, district Jhajjar, Haryana, among ever married females aged 30-59 years. A total of 1615 women were enumerated from three randomly selected sub-centers. Out of these 1359 were interviewed by house to house survey. Among them 664 (49%) consented for per-vaginal examination for Visual Inspection with Acetic acid (VIA), Visual Inspection with Lugol’s Iodine (VILI) and Papanicolaou (Pap) smear at the respective sub-centers. Data was analyzed using SPSS version 17.
Results: Per-vaginal discharge (45.9%) was the most common complaint followed by lower backache (36.6%) and lower abdominal pain (35.0%). VIA was positive in 18.5%; while VILI in 23.2% of study subjects. On cytological examination, in 313 subjects, no significant pathology was detected. Six subjects (0.904%) showed epithelial cell abnormality classified as ASCUS among four cases and one each as LSIL and HSIL.
Conclusions: Low prevalence (0.9%) of epithelial cell abnormalities observed in study confirmed the national estimates for Haryana as low prevalence area for cervical cancers.Metrics
References
Farley J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. GLOBOCAN 2008: Cervical cancer incidence and mortality worldwide in 2008. In: Farley J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM, eds. IARC CaseBase 10. Lyon, France: IARC Press; 2010.
Yang BH. Cervical cancer as a priority for prevention in different world regions: an evaluation using years of life lost. Int J Cancer. 2004;109:418-24.
IARC Screening Group. Cervical cancer. WHO, 2012. Available at: http://screening.iarc.fr/cervicalindex.php.
Basu P, Chowdhury D. Cervical cancer screening & HPV vaccination: a comprehensive approach to cervical control. Indian J Med Res. 2009;130:241-6.
Sankaranarayanan R, Nene BM, Dinshaw KA, Mahe C, Jayant K, Shastri SS, et al. A cluster randomized controlled trial of visual, cytology and human papilloma virus screening for cancer of the cervix in rural India. Int J Cancer. 2005;116:617-23.
Sankaranarayanan R, Wesley RS. A practical manual on visual screening for cervical neoplasia. Lyon, France: IARC Press; IARC technical publication Number 41, 2015. Available at: press@iarc.fr.
IARC. IARC handbooks of cancer prevention. Cervix cancer screening. Vol. 10. Lyon, France: International Agency for Research on Cancer Press; 2005. Available at: http://www.iarc.fr/en/publications/pdfs-online/prev/handbook10/index.php.
Forouzanfar MH, Foreman KJ, Delossantos AM, Lozano R, Lopez AD, Murray CJL, et al. Breast and cervical cancer in 187 countries between 1980 and 2010: a systematic analysis. Lancet. 2011;378:1461-84.
Bhatla N, Gulati A, Mathur SR, Rani S, Anand K, Muwonge R, et al. Evaluation of cervical screening in rural North India. Int J Gynaecol Obstet 2009;105:145-9.
Aswathy S, Quereshi MA, Kurian B, Leelamoni K. Cervical cancer screening: current knowledge & practice among women in a rural population of Kerala, India. Indian J Med Res. 2012;136:205-10.
Meszaros E. Risk factors, knowledge, and beliefs about cervical cancer screening and screening practices among Appalachian women. In: Meszaros E, eds. A Thesis. Ohio: The Ohio State University; 2006.
Singla S, Mathur S, Kriplani A, Agarwal N, Garg P, Bhatla N. Single visit approach for management of cervical intraepithelial neoplasia by visual inspection & loop electrosurgical excision procedure. Indian J Med Res. 2012;135:614-20.
Ghosh P, Gandhi G, Kochhar PK, Zutshi V, Batra S. Visual inspection of cervix with Lugol’s iodine for early detection of premalignant & malignant lesions of cervix. Indian J Med Res. 2012;136:265-71.
Vecchia CL, Francesch S, Decarli A, Fasoli M, Gentile A, Parazzini F, et al. Sexual factors, venereal diseases, and the risk of intraepithelial and invasive cervical neoplasia. Cancer. 1986;58:935-41.
Klomp JM, Boon ME, Van Haaften M, Heintz PM. Cytologically diagnosed Gardnerella vaginalis infection and cervical (pre)-neoplasia as established in population-based cervical screening. Am J Obstet Gynecol. 2008;199:480.e1-5.