Transverse limb defect: a case report

Vidyashree Ganesh Poojari, Muralidhar V. Pai, Akhila Vasudeva, Jayaraman Nambiar


Transverse limb defects are a relatively rare problem (3.5-6.9/10000 births) with a fairly low prenatal detection rate (55%). The possible etiology for this condition could be as part of a genetic condition or amniotic band syndrome. The detection rate can be improved with the use of careful anatomical survey during anomaly scan. In this case report, transverse limb defect was detected in the second trimester. 


Transverse limb defect, Prenatal diagnosis, Termination of pregnancy

Full Text:



Genest DR, Di Salvo D, Rosenblatt MJ, Holmes LB. Terminal transverse limb defects with tethering and omphalocele in a 17 week fetus following first trimester misoprostol exposure. Clin Dysmorphol. 1999;8(1):53-8.

Saeed F, Paramasivam G, Wiechec M, Kumar S. Incidence and outcome of antenatally diagnosed isolated transverse limb defects. Ultrasound Obstet Gynecol. 2009;34(Suppl 1):177-284.

Salomon LJ, Alfirevic Z, Bilardo CM, Chalouhi GE, Ghi T, Kagan KO, et al. ISUOG Practice Guidelines: performance of first-trimester fetal ultrasound scan. Ultrasound Obstet Gynecol. 2013;41:102-13.

Cullen MT, Green J, Whetham J, Salfia C, Gabrielli S, Hobbins JC. Transvaginal ultrasonographic detection of congenital anomalies in the first trimester. Am J Obstet Gynecol. 1990;163:466-76.

Achiron R, Tadmor O. Screening for fetal anomalies during the first trimester of pregnancy: transvaginal versus transabdominal sonography. Ultrasound Obstet Gynecol. 1991;1:186-91.