Burden of eclampsia: a persisting problem in the developing countries

Authors

  • Kavita Babbar
  • Meena Armo Department of Obstetrics & Gynecology, Chhattisgarh Institute of Medical Sciences (CIMS), Bilaspur, Chhattisgarh-495001, India
  • Madhumita Murthy Department of Anaesthesia, Chhattisgarh Institute of Medical Sciences (CIMS), Bilaspur, Chhattisgarh-495001, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20150421

Keywords:

Eclampsia, Burden, Maternal morbidity

Abstract

Background: Hypertensive disorders of pregnancy constitute one of the major threats to maternal health. Eclampsia is still a leading cause of maternal morbidity and mortality in developing countries. This study was carried out to determine the incidence of eclampsia, demographic profile of patients, obstetric outcome, fetal outcome, maternal morbidity and mortality.

Methods: A 5 year retrospective observational study included 521 patients who presented in emergency with eclampsia and admitted between April 2010 and March 2015, in the department of Obstetrics and gynecology, government medical college (Chhattisgarh institute of medical sciences) and tertiary care hospital Bilaspur, Chhattisgarh.

Results: Based on 14,876 pregnancies in the 5 year period in our referral hospital, we estimated an incidence of 3.5%.70.8% were primigravida and 86.4% of patients had no regular antenatal care. Majority of the cases (82.1%) presented as antepartum/intrapartum eclampsia in the age group 20-24 years (65.4%).The patients usually presented at term(62.4%) with 69.7% having vaginal delivery as compared to 30.3% undergoing LSCS. The fetal outcome showed 56.2% live-births, 25.5% had early neonatal death and 13.3% still-born. The complications most commonly observed were puerperal sepsis ( 11 %),oliguria(8.1%), pulmonary edema(5.9%) and maternal mortality as 8.4 %.

Conclusions: Most of the life-threatening eclampsia cases can be prevented by simple awareness and motivation towards antenatal care. In Chhattisgarh state where majority of rural population are tribal, illiterate, living in difficult to reach areas, delay in referral, due to unavailability of clinicians or medical officers in peripheral areas for antenatal examination.The best way to reduce the burden is by creating an awareness, proper antenatal care, timely referral and thus prevent the occurrence of eclampsia.

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References

Mordechai Hallak: Hypertension in pregnancy. High risk pregnancy: management option, Second edition (1999) W.B. Saunders; 639-663.

Magee LA, von Dadelszen P, Chan S, Gafni A, Gruslin A, Helewa M, et al. CHIPS Pilot Trial Collaborative Group. The control of hypertension in pregnancy study pilot trial. Br J Obstet Gynaecol. 2007;114:e13–20.

Ducarme G, Herrnberger S. Eclampsia: retrospective study of 16 cases. Obs and gynecology Fertility. 2009;37(1):11-17.

Ghulmiyyah L, Sibai B. Maternal Mortality From Preeclampsia/Eclampsia Seminars in Perinatology. 2012;36(1):56–9.

Gupte S, Waugh G. Preeclampsia–Eclampsia. Journal of Obstetrics and Gynaecology of India. 2014;64(1):4-13.

Chaturvedi S, Randive B, Mistry N. Availability of treatment for eclampsia in public health institutions in Maharashtra. India. J Health Popul Nutr. 2013;31(1):86-95.

Annual Health Survey 2011-2012 fact: Chhattisgarh office of the Registrar General and Census Commission. Vital statistics division, New Delhi, India.

Rasaly S, Carson-Dewitt. Pre-eclampsia & eclampsia. Gale Encyclopedia of Medicine. 23-40.

Warden M, Euerle B. Pre eclampsia (Toxaemia of pregnancy) emergency Medicine 2003. Updated on April 5 2002.

Sheraz S, Boota M. Shahzad S. Eclampsia. Prof Med J. 2006.13(1):27-31.

Datta MR, Pant L, Kabiraj M, Basu SB. Magnesium sulfate in eclampsia: A safe, efficient and cost-effective approach. J Obst Gynecol India. 2002;52(3):65-8.

Shaheen B. Hassan L, Obaid M. Eclampsia, a major cause of maternal and perinatal mortality: A prospective analysis at a tertiary care hospital of Peshawar. J Pak Med Assoc. 2003;53:346.

Choudhary P. Eclampsia: A hospital based retrospective study. Kathmandu University Medical Journal. 2003;1(4):237-41.

Tuffnell DJ, Jankowisz D, Lindow SW. Outcomes of severe pre-eclampsia/eclampsia in Yorkshire 1999/2003. BJOG: An International Journal of Obstetrics & Gynaecology. 2005;112(7):875-80.

Joshi Suyajna D, Veerendrakumar CM. 'Single Dose MgSo4 Regimen’ for Eclampsia - A Safe Motherhood Initiative. J Clin Diagn Res. 2013;7(5):868–72.

Douglas KA, Redman CW. Eclampsia in the United Kingdom. BMJ. 1994;309:1395.

El Nafaty AU, Melah GS, Massa AA, Audu BM, Nelda M. The analysis of eclamptic Morbidity and Mortality in the Specialist Hospital Gombe, Nigeria. J Obstet gynaecol. 2004;24(2):142–7.

Pradeep MR, Lalitha S. Retrospective Study of Eclampsia in a Teaching Hospital. International Journal of Recent Trends in Science and Technology. 2013;8(3):171-3.

Yaliwal RG, Jaju PB, Vanishree M. Eclampsia and Perinatal Outcome A Retrospective Study in a Teaching Hospital Journal of Clinical and Diagnostic Research. 2011;5(5):1056-9.

Mattar F, Sibai BM. Eclampsia. VIII. Risk factors for maternal morbidity. Am J Obstet Gynecol. 2000;182:307–12.

Gaddi SS, Somegowda. Maternal and perinatal outcome in eclampsia in a district hospital. J Obst Gyn Ind. 2007:57(4):324-26.

Nobis PN. Maternal outcome in eclampsia. Obstet. Gynecol Asia. 2002;6(1):25-8.

Registrar General and Census Commissioner, 2011b. Presentation on Annual Health Survey Fact Sheet Key Findings, Annual Health Survey 2010e11, Ministry of Home Affairs. Government of India, New Delhi.

Ronsmans C, Campbell O. Quantifying the fall in mortality associated with interventions related to hypertensive diseases of pregnancy. BMC Public Health. (2011),11(3).

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Published

2017-02-09

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Original Research Articles