The correlation between full biophysical profile and rapid biophysical profile in antepartum fetal surveillance

Akshay Vedanga Prabhu, Nina Mahale, Ajit Mahale


Background: The aim of this study was to assess the efficiency of rapid biophysical profile in antepartum fetal surveillance and ability to predict adverse perinatal outcome and to compare it with the gold standard full biophysical profile. The objective was to determine the correlation between the rapid biophysical profile (RBP) and the full biophysical profile (FBP) and to compare the individual scores with pregnancy outcomes.

Methods: A prospective study was performed in 153 singleton pregnancies with no fetal anomalies between 34-42 weeks of gestation. All participants received both the standard (FBP) and the new RBP. Abnormal fetal test was defined as having a score of ≤ 6 for FBP or ≤ 2 for RBP. The main outcome measured was Spearman’s correlation coefficient (rs) between both examinations and also between each examination and pregnancy outcomes measured in terms of Apgar scores and NICU (Neonatal Intensive Care Unit) admissions

Results: The data showed a positive correlation between the two tests (rs = 0.62; p < 0.0001). Out of the individual biophysical variables, only NST (Non Stress Test) had a positive correlation with RBP. The sensitivity, specificity, positive predictive value and negative predictive value of RBP in predicting adverse outcomes was found to be 71.4%, 87.1%, 35.7%. 96.8% respectively.

Conclusions: The statistically significant positive correlation between RBP and FBP has been revealed. Due to its simplicity, rapidity, and no need for experienced interpreter, the RBP may be alternatively used as a primary screening antepartum fetal test in the overcrowded obstetric center.


Rapid biophysical profile, Sound provoked fetal movements, Antepartum surveillance

Full Text:



Manning FA, Morrison I, Lange IR, Harman CR, Chamberlain PF. Fetal assessment based on fetal biophysical profile scoring: experience in 12,620 referred high-risk pregnancies. I. Perinatal mortality by frequency and etiology. Am J Obstet Gynecol. 1985;151:343-5.

Tongprasert F, Jinpala S, Srisupandit K, Tongsong T. The rapid biophysical profile for early intrapartum fetal well-being assessment. Int J Gynaecol Obstet. 2006;95:14-7.

Tongsong T, Piyamongkol W, Anantachote A, Pulphutapong K. The rapid biophysical profile for assessment of fetal well-being. J Obstet Gynaecol Res. 1999;25:431-68.

Phattanchindakun B, Boonyagulsrirung T, Chanprapaph P. The correlation in antepartum fetal test between full fetal biophysical profile and rapid biophysical profile. J Med Assoc Thai. 2010;93(7):759-64.

Chousawai S, Tongprasert F, Yanase Y, et al. The efficacy of rapid biophysical profile in predicting poor pregnancy outocmes in suspected intrauterine growth restriction fetuses:preliminary study. J Med Assoc Thai. 2012;95(4):482-6.