DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20150765

Sertoli leydig cell tumor with rare form of presentation

Sasikala Ramraj, Akshya Prabha Venkatakrishnan, Gayathri Mohan

Abstract


Ovarian sex cord stromal cell tumors occur most frequently in the third and fourth decades of life. 75% of these tumors are seen in women younger than 40 yrs. These neoplasms are extremely rare and account for < 0.5% of ovarian cancers. We present a case of 30 yr. old multiparous lady, with abdominal distension and pain, diagnosed with bilateral solid ovarian tumor and underwent staging laparotomy followed by total abdominal hysterectomy with bilateral salpingo oophorectomy and infracolic omentectomy. HPE revealed sertoli leydig cell tumor of intermediate differentiation on both sides. We present this case here for its rare presentation.


Keywords


Sex cord stromal tumors, Sertoli leydig cell tumor, Intermediate differentiation

Full Text:

PDF

References


Zhang HY, Zhu JE, Huang W, Zhu J., clinic pathologic features of ovarian sertoli-leydig cell tumors, International journal of clinical exp. Pathology. 2014;7(10):6956-64.

Kanade US, Dantkale SS, Narkhede RR, Kurawar RR, Bansode SY. Sertoli-Leydig cell tumor of ovary with menorrhagia: A rare case report. Journal of clinical and diagnostic research: JCDR. 2014;8(10); FD18-FD20.

Abu-Zaid A, Azzam A, Alghuneim LA, Metawee MT, Amin T, Al-Hussain TO. Poorly differentiated Ovarian Sertoli-leydig Cell Tumor in a 16-year-old single woman: A Case Report and Literature. Case Reports in Obstetrics and Gynecology. 2013:2013:858501.

Gui T, Cao D, Shen K, Zhang Y, Yu Q, Wan X et al. A clinicopathological analysis of 40 cases of ovarian sertoli leydig cell tumors, Journal of gynecological oncology. 2012;127(2):384-9.

Siqismondi C, Gadducci A, Lorusso D, Candiani M, Breda E, Raspagliesi F et al. Ovarian sertoli leydig cell tumors, a retrospective MITO study, Gynecologic oncology. 2012:125(3);673-6.

Chen L, Tunnell CD, De Petris G. Sertoli leydig cell tumor with heterologous element: a case report and a review of literature, International Journal of Clinical and Experimental Pathology. 2014;7(3):1176-81.

Bhat RA, Lim YK, Chia YN, Yam KL. Sertoli leydig cell tumor of ovary: ananlysis of a single institution database, The Journal of Obstetrics and Gynecology Research. 2013;39(1):305-10.

Sachdeva P, Arora R, Dubey C, Sukhija A, Daga M, Singh DK. Sertoli leydig cell tumor: a rare ovarian neoplasm. Case report and review of literature. Gynecological Endocrinology. 2008:24(4):230-4.

Movahedi Lankarani S, Kurman RJ. Calretinin: a more sensitive but less specific marker than alpha inhibin for ovarian sex cord stromal neoplasms: an immunohistochemical study of 215 cases, The American Journal of Surgical Pathology. 2002;26(11):1477-83.

Demidov VN, Lipatenkova J, Vikhareva O, Van Holsbeke C, Timmerman D, Valentin L. Imaging of gynecological disease: clinical and ultrasound characteristics of sertoli cell tumors, sertoli leydig cell tumor, leydig cell tumors, Ultrasound in Obstetrics and Gynecology. 2008;31(1):85-91.

Cleide Mara Mazzotti de Oliveira Franzin, Maria Lucia Kraft, Daniel Faundes, Luiz Carlos Zeferino, Marcelo Alvarenga, Emilo Francisco Marussi. Detection of ovarian sertoli leydig cell tumors exclusively by colour Doppler sonography, Journal of Ultrasound Med. 2006;25:1327-30.

Thrall MM, Paley P, Pizer E, Garcia R, Goff BA. Patterns of spread and recurrence of sex cord stromal tumors of the ovary, Gynecologic oncology. 2011,122(2):242-5.