Oligohydramnios sequence and a variant of Dandy-Walker syndrome

Authors

  • Prasad Yeshwant Deshmukh Department of Obstetrics & Gynaecology, MGM Medical College, Navi Mumbai, Maharashtra, India
  • Shaifali Kundan Patil Department of Obstetrics & Gynaecology, MGM Medical College, Navi Mumbai, Maharashtra, India
  • B. G. Boricha Department of Obstetrics & Gynaecology, MGM Medical College, Navi Mumbai, Maharashtra, India

Keywords:

Dandy-Walker syndrome, Oligohydramnios sequence, Anomaly scan, Fetal MRI, Fetal autopsy, Poor prognosis

Abstract

Dandy-Walker syndrome is frequently associated with disorders of other areas of the central nervous system, including absence of the area made up of nerve fibers connecting the two cerebral hemispheres (corpus callosum) and malformations of the heart, face, limbs, fingers and toes. In the diagnostic workup, ultrasound is reliable and accurate for making the diagnosis. For diagnostic purposes and confirmation of diagnosis, foetal MRI in utero also has been advocated. Further confirmation may be done with autopsy of neonate after birth. Most of the pregnancies are terminated after antenatal diagnosis on anomaly scan. However if born alive the survival depends on associated anomalies in other systems.

References

Griffiths PD, Paley MN, Whitby EH. Post-mortem MRI as an adjunct to fetal or neonatal autopsy. Lancet. 2005;365:1271-3.

Osenbach RK, Menezes AH. Diagnosis and management of the Dandy-Walker malformation: 30 years of experience. Paediatr Neurosurg. 1992;18:179-89.

Bromley B, Nadel AS, Pauker S, Estroff JA, Benacerraf BR. Closure of the cerebellar vermis: evaluation with second trimester US. Radiology. 1994;193:761-3.

Lavanya T, Cohen M, Gandhi SV. A case of a Dandy-Walker variant: the importance of a multidisciplinary team approach using complementary techniques to obtain accurate diagnostic information. Br J Radiol. 2008;81:245-7.

Downloads

Published

2017-02-10