Study of congenital anomalies of fetus and its outcome in a tertiary care centre
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20150951Keywords:
Congenital malformations, New-born, Still born, antenatal ultrasound, Central nervous systemAbstract
Background: According to WHO Congenital anomalies are defined as structural or functional anomalies, including metabolic disorders which are present at the time of birth. Congenital anomalies are a major health problem accounting for 8% to 15% of perinatal deaths and 13% to 16% of neonatal deaths in India. This study was done to know the frequency, pattern of congenital anomalies and various presentations, which may help to develop strategies for patient counseling and management. The objective of study was to present the spectrum of various congenital anomalies, epidemiological features of pregnant women with anomalous fetus.
Methods: Retrospective, analytical hospital based study of 45 patients who delivered or aborted congenital anomalous baby from a period of 1st Jan 2012 to 31st August 2015. Relevant information regarding maternal age, parity, gestational age, birth weight, sex, and consanguinity antenatal ultrasound was documented.
Results: During the study period 45 congenital anomalies were seen in delivered babies and aborted fetus, 32 (71%) patients were in the age group of 20-29 years. 35 (77%) patients were from rural area and 29 (65%)were unbooked patients. The incidence of congenital malformations was higher among abortions and preterm deliveries. Incidence of congenital anomalies was higher in stillborn. 31 (68%) patients had anomalies diagnosed on antenatal ultrasound. Central nervous system was the most common system involved followed by musculoskeletal system. Anencephaly was the common malformation seen in 12 (27%) patients.
Conclusions: Our study concluded that number of congenital anomalies were more in rural patients and were higher in stillborn. Central nervous system was commonly involved. Early diagnosis, antenatal ultrasonography, proper counseling for this pregnancy and subsequent pregnancy in needed for proper management of the problem.References
Grover N. Congenital malformations in Shimla. Indian J Pediatr. 2000;67:249-51.
Congenital anomalies fact sheet N 370, World health organization. 2014:5.
Kalter H, Warkany J. Medical progress. Congenital malformations: etiologic factors and their role in prevention. N Engl J Med. 1983;308:424-33.
Nelson K, Holmes LB. Malformations due to presumed spontaneous mutations in new-born infants. N Engl J Med. 1989;320:19-23.
Singh A, Gupta RK. Pattern of congenital anomalies in new-borns: a hospital based prospective study. JK Sci. 2009;1:34-6.
Basavanthappa SP, Pejaver R, Srinivasa V, Raghavendra K, Suresh Babu MT. Spectrum of congenital malformations in newborns: in a medical college hospital in South India. Int J Adv Med. 2014;1:82-5.
Bhat V, Babu L. Congenital Malformations at Birth - A Prospective Study from South India. Indian J Pediatr. 1998;65:873-81.
Sachdeva S, Nanda S, Bhalla K, Sachdeva R. Gross congenital malformation at birth in a government hospital. Indian J Public Health. 2014;58:54-6.
Sangeeta Chippa et al. Study of congenital anomalies during pregnancy. International J Recent Trends Sci Tech. 2014;12(1):73.
Chaturvedi P, Banerjee KS. Spectrum of Congenital Malformations in the Newborns from Rural Maharashtra. Indian J Pediatr. 1989;56:501-7.
Parmar A, Rathod SP, Patel SV, Patel SM. A Study of Congenital Anomalies in Newborn. NJIRM. 2010;1(1):13.
Gagnon A. Evaluation of prenatally diagnosed structural congenital anomalies. J Obstet Gynaecol Can. 2009;31(9):875-81.
Gupta S, Gupta P, Jagdish S. Study on incidence of various systemic congenital malformations and their association with maternal factors national journal of medical research Volume. 2012;2(1):19-21.
Fatema K, Begum F, Akter N, Zaman SM. Major congenital malformations among the newborns in BSMMU hospital. Bangladesh Med J. 2011;40:7-12.
