Seroprevalence of HIV in ANC clinic attendees and utilization of PPTCT services at a tertiary care hospital of western Rajasthan, India

Swati Mehta, Balgopal Singh Bhati, Lokesh Mehta


Background: Human immunodeficiency virus (HIV) infection in pregnant women has an important role in its spread to paediatric population by means of vertical transmission. Effective utilization of PPTCT services can reduce this spread. This study aims to determine seroprevalence of HIV in antenatal women, demographic factors of seropositive women and utilization of PPTCT services to minimize the risk of mother to child transmission.

Methods: A retrospective study was done among pregnant women attending antenatal clinic of a tertiary care hospital within a period of two years from November 2013 to October 2015. Pre-test counselling, HIV testing, and post-test counselling were done as per NACO guidelines. Antiretroviral prophylaxis was given to seropositive women and their children. Analysis of demographic data of seropositive women and assessment of utilization of PPTCT services was done.

Results: Out of 40,913 new antenatal registrations 26,803 (65.58%) women attended pre test counselling and 24716(60.41%) of them accepted HIV testing. Thirty-eight women were found to be seropositive with a seroprevalence rate of 0.16%. Majority of seropositve women were young primigravida, illiterate housewives belonging to rural area. Eight out of 33 partners of seropositive women tested, were found to be seronegative. Out of the 38 seropositive women, 4(10.52%) opted for pregnancy termination, and 31(81.57%) had delivery in our institution. All mother and baby pairs received antiretroviral prophylaxis.

Conclusions: Seroprevalence of HIV infection in antenatal women is relatively low in this region than the national average and acceptance of therapeutic interventions to reduce the mother to child transmission is high. There is scope to improve acceptance of counselling and testing of HIV.


Antenatal, Human immunodeficiency virus, PPTCT, Seroprevalence

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UNAIDS. 90-90-90: an ambitious treatment target to help end the AIDS epidemic. Geneva: UNAIDS; 2014.

NACO National HIV counselling and testing services (HCTS) guidelines; 2017.

Department of AIDS Control. Ministry of Health and Family Welfare. NACO Annual Report 2010-2011.

Department of AIDS Control. Ministry of Health and Family Welfare. NACO Annual Report 2015-2016.

Zaba B, Boerma T, White R, Monitoring the AIDS epidemic using HIV prevalence data among young women attending antenatal clinics: prospects and problems. AIDS Lond Engl. 2000;14(11):1633-45.

Boerma JT, Ghys PD, Walker N, Estimates of HIV-1 prevalence from national population-based surveys as a new gold standard. Lancet Lond Engl. 2003;362(9399):1929-31.

NACO Updated Guidelines For Prevention of Parent to Child Transmission of HIV using Multidrug Antiretroviral Therapy in India; 2017.

Shah I. HIV/AIDS in children. In: Parthasarathy A, editor. Indian Academy of Paediatrics - Textbook of Paediatric Infectious Diseases. New Delhi: Jaypee Brothers. 2013:336-45.

NACO. Prevention of Parent to Child Transmission [PPTCT]. 2017. Available from:

Centre for Disease Control. Divisions of HIV/Aids Prevention. Routine Perinatal Testing The Opt-Out Approach Questions and answers. 2004.

Rajasthan State AIDS Control Society. ICTC. Available from:

Joshi U, Kadri A, Bhojiya S. Prevention of parent to child transmission services and interventions, coverage and utilization: A cohort analysis in Gujarat, India. Indian J Sex Transm Dis. 2010;31:92-8.

Sinha A, Roy M. An ICMR task force study of Prevention of Parent to Child Transmission (PPTCT) service delivery in India. Indian J Public Health. 2008;52:200-2.

Kulkarni S, Doibale M. Trend of seroprevalence of HIV among antenatal clinic attendees at a tertiary care hospital. Int J Basic Appl Med Sci. 2013;3(1):257-62.

Parameshwari S, Jacob MS, Vijaykumari JJ, Shalini D, Sushil MK, Shivkumar MR. A programme on prevention of mother to child transmission of HIV at Government hospital. Tiruchegonda taluk, Namakkal district. Ind J Com Med. 2009;34:261-3.

Chaudhuri S, Mundle M, Konar H, Das C, Talukdar A, Ghosh US. Utilization of therapeutic intervention to prevent mother to child transmission of HIV in a teaching hospital in Kolkata, India. J Obstet Gynaecol Res. 2010; 36:619-25.

Kour G, Gupta S, Khajuria R. Seroprevalence of human immunodeficiency virus and various risk factors responsible for spread of human immunodeficiency virus in pregnant women in Jammu, India. Int J Reprod Contracept Obstet Gynecol. 2016;5:3552-5.

Mehta KD, Antala S, Mistry M, Goswami Y. Seropositivity of hepatitis B,hepatitis C, syphilis, and HIV in antenatal women in India. J Infect Dev Ctries. 2013; 7(11):832-37.

Sibia P, Kumar A. Seroprevalence of Human Immunodeficiency Virus among Antenatal Women in One of the Institute of Northern India. Journal of Clinical and Diagnostic Research. 2016;10(9):8-9.

NACO A Technical Brief of HIV sentinel surveillance 2014-15. Available from:

Kwatra A, Bangal VB, Shinde K, Padaliya K. HIV seroprevalence among the pregnant population and utilisation of integrated counselling and training centre facilities at a teaching hospital in Rural Maharashtra. Austral Med J. 2011;4(10):566-70.

Ukey PM, Akulwar SL, Powar RM. Seroprevalence of human immunodeficiency virus infection in pregnancy in a tertiary care hospital. Indian J Med Sci. 2005;59(9):382-87.

Hussain T, Kulshreshtha KK, Yadav VS. HIV infection among pregnant women attending an integrated counseling & testing centre at Agra: comparison with studies in other regions of India. Hussain T et al. Int J Reprod Contracept Obstet Gynecol. 2016;5(1):90-7.

Chaudhuri S, Bose S, Talukdar A, Ghosh US. Seroprevalence and utilization of therapeutic intervention in PPTCT services in a teaching hospital in Kolkata. J Obstet Gynecol India. 2007;57(3):251-6.

Tayade S, Shivkumar PV, Karambelkar m. hiv seroprevalence in antenatal attendees and utilization of integrated counseling and testing centre (ictc) services a study in a tertiary medical institute of rural area. Int J Biomed Res. 2012;3(4):214-20.