Clinical study of vesicular mole

Authors

  • Harshada Subhash Thakur Department of Obstetrics and Gynecology, Seth Gordhandas Sunderdas Medical College, King Edward Memorial Hospital, Mumbai, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-1770.ijrcog20170959

Keywords:

Complete, Partial, Theca lutein cysts

Abstract

Background: Vesicular mole is an abnormal condition where there is partly degeneration and partly hyperplastic changes in the young chorionic villi. The purpose of this study is clinical presentation of molar pregnancy, serum β-hCG regression curve and further management.

Methods: This was a prospective study undertaken in the Department of Obstetrics and Gynaecology at the tertiary care center for the study period from October 2007 to May 2009 approved by ethical committee.

Results: Incidence of vascular mole was 2.5 per 1000 deliveries. 46.15% women were in the age group 20-24 years, 33.33% in the age group 25-29 years and 20.51% were in the teenage group. 58.97% women were between gravidity 2-4.

Conclusions: There was a significant association of serum β-hCG >1,00,000 mlU/ml with theca lutein cysts >6 cm. 11.76% women with complete mole had elevated TFT while not a single woman with partial mole had elevated TFTs.

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References

Chhabra S, Qureshi A. The Journal of Obstetrics and Gynaecology of India. 2007;57(2):124-7.

Jonathan S. Berek. Berek and Novak Ganaecology. 14th Edition; 2007:2151-2176.

Sekharan PK. The management of gestational trophoblastic neoplasia. FOGSI-ICOG consensus statement, India, 2006. Available from: http://www.icogonline.org/images/pdf/gcpguidelines/Gestational_T_Dis.pdf

Kaye DK. Gestational trophoblastic disease following complete hydatidiform mole in Mulago hospital, Kampala, Uganda. African Health Sci. 2002;2(2):47-51.

Bandy LC, Clarke-Pearson DL, Charles B. Hammond CB. Malignant potential of gestational trophoblastic disease at extreme ages of reproductive life. Obstet Gynecol. 1984 Sep;64(3):395-9.

Ong HC, Chong L. Clinical observations of hydatidiform moles in a Malaysian Hospital. Singapore Med J. 1978;19(1):33-6.

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Published

2017-03-30

How to Cite

Thakur, H. S. (2017). Clinical study of vesicular mole. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 6(4), 1211–1214. https://doi.org/10.18203/2320-1770.ijrcog20170959

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Section

Original Research Articles