Study of feto-maternal outcome in patients of jaundice in third trimester of pregnancy
DOI:
https://doi.org/10.18203/2320-1770.ijrcog20151294Keywords:
Jaundice in pregnancy, Maternal morbidity and mortalityAbstract
Background: Jaundice in pregnancy is an important medical disorder, more commonly seen in developing countries than developed ones. It comprises of a formidable list of complications that may adversely affect the pregnant woman and her fetus. Objective of current study was to study causes and feto-maternal outcome in pregnancies with jaundice in 3rd trimester.
Methods: This was a retrospective study of 49 patients admitted in department of Obstetrics & Gynaecology at a tertiary care hospital with jaundice in 3rd trimester of pregnancy during the period from September 2008 to September 2010.
Results: Out of 9972 deliveries, 49 patients were admitted with jaundice in 3rd trimester of pregnancy. Out of them 91.1% patients delivered. Vaginal delivery occurred in 82.2% and Cesarean section done in 17.7%. Preterm delivery occurred in 68.8%, low birth weight (LBW) was found in 82.2%, perinatal mortality occurred in 34.6% and maternal mortality occurred in 16.3% of patients.
Conclusions: Jaundice in 3rd trimester of pregnancy leads to preterm delivery, fetal distress, intra uterine fetal death (IUFD) and high perinatal & maternal morbidity and mortality. Early diagnosis & aggressive management at tertiary care center help in reducing maternal & perinatal morbiditiy and mortality.References
Hay J, Eileen. Liver disease in pregnancy. Hepatology. 2008;47(3):1067-76.
Nagaria Tripti, Agrwal Sarita. Fetomaternal outcome in Jaundice during Pregnancy. J Obstet Gynecol India. 2005;55:424-7.
Oladokun A, Otegbayo JA, Adeniyi AA. Maternal & fetal outcome of Jaundice in pregnancy at university college Hospital, Ibadan. Niger J Clin Pract. 2009;12(3):277-80.
Parveen T, Begum F, Akhtar N. Feto-maternal outcome of jaundice in pregnancy at tertiary care hospital. Mymensingh Med J. 2015;24(3):528-36.
Yeul Veronica Irene, Kaur Vaneeta. HEV in pregnancy. J Obstet Gynecol. India. 2006;56:146-8.
Safary A. Perspectives of vaccination against hepatitis E. Intervirology. 2001;44:162-3.
Kumar A, Beniwal B, Kar P. Hepatitis E in pregnancy. Obstetric Gynecol Surv. 2005;60:7-8.
Ray Alokananda, Tata Rashne J, Balsara. Cholestasis of pregnancy. J of Gynecol India. 2005;55:247-50.
U Rathi, Bapat, M Rathi, Abraham Effect of liver disease on maternal and fetal outcome - a prospective study. Indian J Gastroenterol. 2007;26(2):59-63.
Trivedi SS, Goyal U, Gupta U. A study of maternal mortality due to viral hepatitis. J Obstet Gynecol India. 2003;53:551-3.
