Maternal and foetal outcome of eclampsia in a referral hospital

Mousumi Das Ghosh, Vinita Singh, Alokananda Ray


Background: Eclampsia is a life-threatening condition, common in developing countries with high fatality rate. It is a cause of maternal and foetal mortality and morbidity. The aim of the study is to determine the maternal and foetal outcome in Tata Main Hospital, Jamshedpur, Jharkhand, India.

Methods: All cases of eclampsia were analysed from January 2012 to December 2014 from admission to discharge or death of the patient.  Age, parity, antenatal care, interval between attack and admission, blood pressure on admission, gestational age and mode of delivery were  taken into account. There were 135 cases of eclampsia out of 14572 deliveries. Only singleton pregnancies were analysed.

Results: The incidence of antepartum eclampsia was 84.4%, intrapartum 3% and postpartum 12.5 %. 83% patients were primigravida, 33% less than 20 yrs,42% had no antenatal checkup and 45% had < 4 visits. Only 15% patients received magnesium sulphate before referral to the hospital. There were four maternal deaths and twenty-one perinatal deaths. Eleven patients needed ventilatory support, four developed pulmonary oedema,  two patients had respiratory depression and three patients had renal failure.

Conclusions: Hypertensive disease in pregnancy requires proper antenatal care, early recognition and referral, adequate treatment and timely delivery.


Eclampsia, Foetal, Maternal

Full Text:



Ghulmiyyah L, Sibai B. Maternal Mortality from pre-eclampsia/eclampsia. Semin Perinatol. 2012;36(1):56-9.

Lal AK, Gao W, Hibbard JU. Eclampsia: maternal and neonatal outcomes: Int J Women Cardiovascular Health. 2013; 3;186-90.

Roy J, Mitra JK, Pal A. Magnesium sulphate versus Phenytoin in eclampsia- maternal and foetal outcome- a comparative study. AMJ. 2013;6(9)483-95.

Seal SL, Ghosh D, Kamilya G. Does route of delivery affect maternal and perinatal outcome in women with eclampsia? A randomized controlled pilot study. Am J Obstet Gynecol. 2012;206:484.e1-7.

The millennium development goals report 2014, United Nations; New York: 2014.

Adamu AN. Pregnancy outcome in women with eclampsia at a tertiary centre in northern Nigeria: Afr J Med Med Sci. 2012:41(2):211-9.

Akhtar R, Ferdous A, Bhuiyan SN. Maternal and fetal outcome of eclamptic patients in a tertiary hospital. Bangladesh J Obstet Gynaecol. 2011;26(2):77-80.

Joshi SD, Veerendrakumar CM. Single dose MgSo4 Regimen for Eclampsia- A Safe Motherhood Initiative. J Clin Diagnost Res. 2013;7(5):868-72.

George IO, Jeremiah I. Perinatal outcome of babies delivered to eclamptic mothers: a prospective study from a Nigerian tertiary hospital. Int J Biomed Sci. 2009;5(4):390-4.

Bailit JL, Grobman WA, McGee P, Reddy UM, Wapner RJ, Varner MW, et al. Is the use of protocols for obstetric care associated with better outcomes? Am J Obstet Gynaecol. 2015;213(1):86