Brenner tumor of ovary: an incidental finding: a case report


  • Bhanwar Singh Jodha Department of Obstetrics and Gynecology, Umaid Hospital, Regional Institute of Maternal and Child Health, Dr. S. N. Medical College, Jodhpur, Rajasthan, India
  • Richa Garg Department of Obstetrics and Gynecology, Umaid Hospital, Regional Institute of Maternal and Child Health, Dr. S. N. Medical College, Jodhpur, Rajasthan, India



Brenner tumor, Ovarian neoplasm, Ultrasonography


Brenner tumor of the ovary is very rare, mostly benign, small, and unilateral. Malignant brenner tumor is much rarer. Malignant brenner tumor of ovary closely resembles the transitional cell carcinoma of ovary. These tumors are believed to arise from urothelial metaplasia of ovarian surface epithelium. However the latter has a worse prognosis. Here we present a case of Brenner tumor of ovary in a postmenopausal woman treated surgically and its features are briefly discussed.


Benson RC. Diagnosis and treatment. Current Obstet Gynaecol. 1976;1:236.

Sen U, Sankaranarayanan R, Mandal S, Romana AV, Parkin DM, Siddique M. Cancer patterns in Eastern India: the first report of Kolkata cancer registry. Int J Cancer. 2002;100:86-91.

Tortulero L, Mitchell FM, Rhodes HE. Epidemidology and screening of ovarian cancer. Obstet Gynaecol Clin North Amer. 1994;21:63-75.

Rashid S, Sarwas G, Ali A. A Clinicopathological study of ovarian cancer. Mother Child. 1998;36:117-25.

Hemalatha AL, Konanahalli P. Bilateral malignant Brenner tumor of ovary. J Obstet Gynecol India. 2005;55:81-2.

Ceausu M, Terzea D, Georgescu A, Dobrea C, Mihai M, Iosif C, et al. Transitional cell tumors of the ovary: a compact group with a heterogeneoushistological and immunophenotypical pattern. Rom J Morphol Embryol. 2008;49:513-6.

Vranes HS, Klaric P, Benkovik LB, Pirkic A. Brenner tumor of the ovary. Acta Clin Croat. 2005;44:271-3.

Marwah N, Mathur SK, Marwah S, Singh S, Karwasra RK, Arora B. Malignant Brenner tumour- a case report". Indian J Pathol Microbiol. 2005;48(2): 251-2.

Athey PA, Siegel MF. Sonographic features of Brenner tumor of the ovary. J Ultrasound Med. 1987;6(7):367-72.

Green GE, Mortele KJ, Glickman JN, Benson CB. Brenner tumors of the ovary: sonographic and computed tomographic imaging features. J Ultrasound Med. 2006;25(10):1245-51.

Caccamo D, Socias M, Truchet C. Malignant Brenner tumor of the testis and epididymis. Arch Pathol Lab Med. 1991;115(5):524-7.

Joh K, Aizawa S, Ohkawa K, Dohzono H, Aida S, Ohgoshi E. Case report of a malignant Brenner tumor with hyperestrogenism. Pathol Int. 1995;45:75-84.

de Lima GR, de Lima OA, Baracat EC, Vasserman J, Burnier M. Virilizing Brenner tumor of the ovary: case report. Obstet GynecoI. 1989;73:895-8.

Rose PG, Reale FR, Longcope C, Hunter RE. Prognostic significance of estrogen and progesterone receptors in epithelial ovarian cancer. Obstet Gynecol. 1990;76:258-63.

Harding M, Cowan S, Hole D, Cassidy L, Kitchener H, Davis J, et al. Estrogen and progesterone receptors in ovarian cancer. Cancer. 1990;65:486-91.

Moon WJ, Koh BH, Kim SK. Brenner tumor of the ovary: CT and MR findings. J Comput Assist Tomogr. 2000;24:72-6.

Takahama J, Ascher SM, Hirohashi S, Takewa M, Ito T, Iwasaki S. Borderline Brenner tumor of the ovary: MRI findings. Abdom Imaging. 2004;29:528-30.

Eichhorn JH, Young RH. Transitional cell carcinoma of the ovary: A morphologic study of 100 cases with emphasis on differential diagnosis. Am J Surg Pathol. 2004;28:453-63.

Von Numbers CA. A contribution to case knowledge and histology of Brenner tumor, do malignant forms of the Brenner tumor also occur? Acta Obstet Gynecol Scand. 1945;2 Suppl:114-27.

Hull MG, Campbell GR. The malignant Brenner tumor. Obstet Gynecol. 1973;42:527-34.

Borah T, Mahanta RK, Bora BD, Saikia S. Brenner tumor of ovary: An incidental finding. J Midlife Health. 2011;2:40-1.






Case Reports